Abstract
Evidence from both epidemiologic and pharmacologic investigations into the biology of attention deficit disorder suggests that abnormalities in neurotransmitter function exist in children with attention deficit disorder. This article reviews this evidence and discusses the limitations imposed upon such clinical investigations.
MeSH terms
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Attention Deficit Disorder with Hyperactivity / drug therapy
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Attention Deficit Disorder with Hyperactivity / metabolism*
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Child
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Dextroamphetamine / therapeutic use
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Dopamine / metabolism
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Humans
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Methoxyhydroxyphenylglycol / metabolism
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Methylphenidate / therapeutic use
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Norepinephrine / metabolism
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Serotonin / metabolism
Substances
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Methylphenidate
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Serotonin
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Methoxyhydroxyphenylglycol
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Dextroamphetamine
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Dopamine
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Norepinephrine