Physostigmine and haloperidol treatment of acute phencyclidine intoxication

Am J Psychiatry. 1982 Apr;139(4):508-10. doi: 10.1176/ajp.139.4.508.

Abstract

Twenty-four patients with phencyclidine intoxication were treated with either physostigmine (2 mg i.m.) or haloperidol (5 mg i.m.) based on the presence of delusions and/or hallucinations. Several symptoms subsequently improved. Schizophreniform symptoms showed substantial improvement with haloperidol.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Female
  • Haloperidol / therapeutic use*
  • Humans
  • Male
  • Phencyclidine Abuse / drug therapy*
  • Phencyclidine Abuse / psychology
  • Physostigmine / therapeutic use*
  • Psychiatric Status Rating Scales

Substances

  • Physostigmine
  • Haloperidol