Abstract
Objective:
The authors' goal was to determine whether higher doses of haloperidol improve antipsychotic response.
Method:
During a 2-week, double-blind, randomized fixed-dose study, 24 psychotic patients were given 4, 10, or 40 mg/day of haloperidol.
Results:
No clinically relevant difference between groups in favor of the higher antipsychotic doses could be detected.
Conclusions:
Doses of 4 mg/day of haloperidol appear to be as effective as higher doses in the treatment of psychosis.
Publication types
-
Clinical Trial
-
Randomized Controlled Trial
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adult
-
Dose-Response Relationship, Drug
-
Double-Blind Method
-
Drug Administration Schedule
-
Female
-
Haloperidol / administration & dosage
-
Haloperidol / therapeutic use*
-
Humans
-
Male
-
Psychiatric Status Rating Scales
-
Psychotic Disorders / diagnosis
-
Psychotic Disorders / drug therapy*
-
Psychotic Disorders / psychology
-
Schizophrenia / diagnosis
-
Schizophrenia / drug therapy
-
Treatment Outcome