Abstract
The Stroop Colour-Word Test (SCWT) and the Verbal Fluency Test (VFT), two tests that have been suggested to be particularly sensitive to prefrontal dysfunction, were administered to 23 severely depressed in-patients. Both tests were impaired in patients at inclusion, but only verbal fluency normalized with successful treatment of depression. VFT impairment is consistent with the hypothesis of a left prefrontal cortex dysfunction in depression. Moreover, the persistence of an impaired performance on SCWT in patients at discharge suggests that a selective attention deficit may persist in patients beyond a clear clinical improvement.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Attention / physiology
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Bipolar Disorder / diagnosis
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Bipolar Disorder / physiopathology*
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Bipolar Disorder / psychology
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Brain Damage, Chronic / diagnosis
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Brain Damage, Chronic / physiopathology
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Brain Damage, Chronic / psychology
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Color Perception / physiology
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Depressive Disorder / diagnosis
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Depressive Disorder / physiopathology*
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Depressive Disorder / psychology
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Discrimination Learning / physiology
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Dominance, Cerebral / physiology
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Female
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Follow-Up Studies
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Humans
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Male
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Mental Recall / physiology
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Middle Aged
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Neurocognitive Disorders / diagnosis
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Neurocognitive Disorders / physiopathology*
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Neurocognitive Disorders / psychology
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Neuropsychological Tests*
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Pattern Recognition, Visual / physiology
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Personality Assessment
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Prefrontal Cortex / physiopathology*
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Psychomotor Performance / physiology
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Semantics
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Verbal Behavior / physiology
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Wechsler Scales