Abstract
The incidence of in-hospital stroke complicating acute myocardial infarction is approximately 1%. This rate is largely unaffected by thrombolytic therapy. Large myocardial infarctions, anterior wall involvement, prior stroke, and increasing age are risk factors for ischemic stroke. Left ventricular thrombi commonly occur with anterior wall infarctions. There is some evidence that anticoagulation reduces their incidence and uncontrolled studies suggest that anticoagulation may reduce the risk of embolization. Left ventricular aneurysms have a low rate of embolization and do not require systemic anticoagulation. Treatment of acute myocardial infarction with t-PA and anisoylated plasminogen streptokinase activator complex are associated with a higher risk of stroke than treatment with streptokinase; this excess risk is attributable to an increased rate of cerebral hemorrhages.
MeSH terms
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Brain / physiopathology
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Brain Diseases / complications
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Brain Diseases / diagnosis
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Brain Diseases / physiopathology
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Cerebrovascular Disorders / complications
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Cerebrovascular Disorders / diagnosis
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Cerebrovascular Disorders / physiopathology
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Coronary Aneurysm / complications
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Coronary Aneurysm / diagnosis
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Coronary Aneurysm / physiopathology
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Coronary Disease / complications
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Coronary Disease / diagnosis
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Coronary Disease / physiopathology*
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Coronary Thrombosis / complications
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Coronary Thrombosis / diagnosis
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Coronary Thrombosis / physiopathology
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Electrocardiography
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Female
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Heart / physiopathology*
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Humans
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Intracranial Embolism and Thrombosis / complications
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Intracranial Embolism and Thrombosis / diagnosis
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Intracranial Embolism and Thrombosis / physiopathology*
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Male
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Myocardial Infarction / complications
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Myocardial Infarction / diagnosis
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Myocardial Infarction / physiopathology*