Cognitive impairment in adolescents with schizophrenia

Am J Psychiatry. 1997 Nov;154(11):1613-5. doi: 10.1176/ajp.154.11.1613.

Abstract

Objective: The purpose of this study was to determine whether adolescent schizophrenia is characterized by neuropsychological deficits.

Method: The performance on a battery of neuropsychological tests of 17 adolescents with schizophrenia (mean age = 15.71 years) was compared with that of 17 normal adolescents (mean age = 15.12 years).

Results: Compared with the normal subjects, the patients were impaired on 10 of the 13 measures; larger effect sizes were shown for measures involving working memory and attention than for those involving secondary memory, generative naming, and executive functions.

Conclusions: Adolescents with schizophrenia have generalized cognitive dysfunction, which is most apparent on tests of attention and working memory.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Attention
  • Cognition Disorders / diagnosis*
  • Female
  • Humans
  • Intelligence Tests
  • Male
  • Memory
  • Neuropsychological Tests / statistics & numerical data
  • Schizophrenia / diagnosis*
  • Schizophrenic Psychology*