User profiles for Abraham Nunes
 | Abraham NunesDepartment of Psychiatry, Dalhousie University Verified email at dal.ca Cited by 1043 |
[HTML][HTML] Using structural MRI to identify bipolar disorders–13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective
biological markers, such as those based on brain imaging, could aid in clinical management …
biological markers, such as those based on brain imaging, could aid in clinical management …
[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
…, MA Laansma, J Leerssen, U Lueken, A Nunes… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …
[HTML][HTML] The definition and measurement of heterogeneity
Heterogeneity is an important concept in psychiatric research and science more broadly. It
negatively impacts effect size estimates under case–control paradigms, and it exposes …
negatively impacts effect size estimates under case–control paradigms, and it exposes …
Prediction of lithium response using clinical data
A Nunes, R Ardau, A Berghöfer… - Acta Psychiatrica …, 2020 - Wiley Online Library
Objective Promptly establishing maintenance therapy could reduce morbidity and mortality
in patients with bipolar disorder. Using a machine learning approach, we sought to evaluate …
in patients with bipolar disorder. Using a machine learning approach, we sought to evaluate …
The potential role of stimulants in treating eating disorders
Background Many individuals with eating disorders remain symptomatic after a course of
psychotherapy and pharmacotherapy; therefore, the development of innovative treatments is …
psychotherapy and pharmacotherapy; therefore, the development of innovative treatments is …
What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …
Efficacy and cost-effectiveness of intensive short-term dynamic psychotherapy for treatment resistant depression: 18-Month follow-up of the Halifax depression trial
Background Depressed patients with chronic and complex health issues commonly relapse;
therefore, examining longer-term outcomes is an important consideration. For treatment …
therefore, examining longer-term outcomes is an important consideration. For treatment …
Familial traits of bipolar disorder: A systematic review and meta‐analysis
Background Genetic studies of bipolar disorder (BD) have shown varied results, which is in
part because of the heterogeneity of the disorder. Identifying clinical phenotypes of BD could …
part because of the heterogeneity of the disorder. Identifying clinical phenotypes of BD could …
[HTML][HTML] Differential characteristics of bipolar I and II disorders: a retrospective, cross-sectional evaluation of clinical features, illness course, and response to treatment
Background The distinction between bipolar I and bipolar II disorder and its treatment
implications have been a matter of ongoing debate. The aim of this study was to examine …
implications have been a matter of ongoing debate. The aim of this study was to examine …
[HTML][HTML] Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder
Predicting lithium response (LiR) in bipolar disorder (BD) may inform treatment planning, but
phenotypic heterogeneity complicates discovery of genomic markers. We hypothesized that …
phenotypic heterogeneity complicates discovery of genomic markers. We hypothesized that …
