Bipolar disorder (BD) is a lifelong neuropsychiatric disorder that exerts a substantial
personal and public health toll, an elevated lifetime risk of suicide, 1 and a remarkable …

Neuropsychiatric disorders are currently defined by behavioral criteria, and the broader
experience of patients who meet the same diagnostic criteria can vary widely. This range of …

Background The latest genetic analyses have identified multiple genetic loci that contribute
to risk of bipolar disorder (BD), yet non-European populations are underrepresented, and …

BackgroundBipolar disorder (BD) shows heterogeneous illness presentation both cross-
sectionally and longitudinally. This phenotypic heterogeneity might reflect underlying …

Overall Abstract Bipolar disorder is a heterogeneous and multidimensional condition with a
complex time course. The past generation of large-scale collaborative research has focused …

Bipolar disorder (BD) is a chronic psychiatric disorder with high morbidity and mortality,
deserving of efforts to understand who are at highest risk for developing this disorder. So far …

There is an increasing body of literature fuelled by advances in high-resolution structural
MRI acquisition and image processing techniques which implicates subtle neuroanatomical …

Bipolar disorder (BD) is a heritable mental illness with complex etiology. We performed a
genome-wide association study (GWAS) of 41,917 BD cases and 371,549 controls of …

Genetic factors are important in the etiology of bipolar disorder (BD). However, first-degree
relatives of BD patients are at risk for a number of psychiatric conditions, most commonly …

The apparently progressive nature of a considerable proportion of cases of bipolar disorder
(BD) has been acknowledged in recently proposed clinical staging models. This has been …