Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible
rewards that involve the striatal dopaminergic system. Using the neurochemical specificity of […

Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape emergent …

Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour,
attention, and sensorimotor integration 1 , 2 . Binding of the radioligand 11 C-labelled …

Parkinson’s disease varies widely in clinical manifestations, course of progression and biomarker
profiles from person to person. Identification of distinct Parkinson’s disease subtypes is …

Publisher Summary Obesity is caused by the consumption of excess calories. As such, it
can be viewed as a failure of homeostatic systems that control body weight or, more …

We performed successive H 2 15 O-PET scans on volunteers as they ate chocolate to beyond
satiety. Thus, the sensory stimulus and act (eating) were held constant while the reward …

Mesolimbic dopamine is thought to play a role in the processing of rewards. However, animal
studies also demonstrate dopamine release in response to aversive stressful stimuli. Also, …

Seven healthy subjects underwent two [ 11 C]raclopride positron emission tomography (PET)
scans, one following a 16-h fast and the other after consumption of a favorite meal (…

The Wisconsin Card Sorting Task (WCST) has been used to assess dysfunction of the
prefrontal cortex and basal ganglia. Previous brain imaging studies have focused on identifying …

Dopamine is implicated in movement, learning, and motivation, and in illnesses such as
Parkinson’s disease, schizophrenia, and drug addiction. Little is known about the control of …