Multidimensional predictors of negative symptoms in antipsychotic-naive first-episode psychosis

A Toll, L Blanco-Hinojo, D Bergé, X Duran… - Journal of Psychiatry and …, 2022 - jpn.ca
Background: Despite a large body of schizophrenia research, we still have no reliable
predictors to guide treatment from illness onset. The present study aimed to identify baseline …

Persistent negative symptoms in first-episode psychosis: early cognitive and social functioning correlates and differences between early and adult onset

O Puig, I Baeza, E de la Serna, B Cabrera… - The Journal of …, 2017 - psychiatrist.com
Objective: To characterize the early cognitive and social functioning characteristics of a
sample of first-episode psychosis patients with and without persistent negative symptoms …

Identifying persistent negative symptoms in first episode psychosis

CL Hovington, M Bodnar, R Joober, AK Malla… - BMC psychiatry, 2012 - Springer
Background Although persistent negative symptoms (PNS) are known to contribute
significantly to poor functional outcome, they remain poorly understood. We examined the …

Negative symptom dimensions in first episode psychosis: Is there a difference between schizophrenia and non‐schizophrenia spectrum disorders?

L Pelizza, S Azzali, F Paterlini… - Early Intervention in …, 2021 - Wiley Online Library
Aim Identifying discrete dimensions that underline negative symptoms in First Episode
Psychosis (FEP) could improve the understanding and the treatment of such invalidating …

Cognitive and global functioning in patients with First-episode psychosis stratified by level of negative symptoms. A 10-year follow-up study

MJ Engen, A Vaskinn, I Melle, A Færden… - Frontiers in …, 2022 - frontiersin.org
Negative and cognitive symptoms are core features of schizophrenia that are correlated in
cross-sectional designs. To further explore the relationship between these critical symptom …

Subtyping negative symptoms in first-episode psychosis: contrasting persistent negative symptoms with a data-driven approach

J Unrau, OP du Sert, R Joober, A Malla, M Lepage… - Schizophrenia …, 2022 - Elsevier
Persistent negative symptoms (PNS) are linked to poor functional outcomes and may be
primary or caused by secondary factors. Although several studies have examined PNS in …

Dorsolateral prefrontal lobe volume and neurological soft signs as predictors of clinical social and functional outcome in schizophrenia: A longitudinal study

RV Behere - Indian journal of psychiatry, 2013 - journals.lww.com
Schizophrenia is a disorder with variable outcome and the ability to predict the outcome has
important clinical utility. Neurological soft signs (NSS) and dorsolateral prefrontal cortex …

Early-stage negative symptom trajectories and relationships with 13-year outcomes in first-episode nonaffective psychosis

WC Chang, RWH Ho, JYM Tang… - Schizophrenia …, 2019 - academic.oup.com
Negative symptoms are a key treatment target in early psychosis intervention. There is a
paucity of research examining longitudinal course of negative symptoms across the initial …

Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis

WC Chang, CFC Lau, SSI Chan, CLM Hui… - Psychiatry …, 2016 - Elsevier
Negative symptoms are a core psychopathological dimension of psychotic disorders.
Previous research on primary negative symptoms (PNS) mostly focused on chronic samples …

Linking persistent negative symptoms to amygdala–hippocampus structure in first-episode psychosis

C Makowski, M Bodnar, JJ Shenker, AK Malla… - Translational …, 2017 - nature.com
Early persistent negative symptoms (PNS) following a first episode of psychosis (FEP) are
linked to poor functional outcome. Reports of reduced amygdalar and hippocampal volumes …