Recent studies have provided evidence for a functional impairment of γ-aminobutyric acid (GABA)-containing
interneurons in the prefrontal cortex of schizophrenics. This evidence …

Background: Postmortem studies have provided evidence for abnormalities of the γ-aminobutyric
acid (GABA)-ergic system in schizophrenia, including deficits of GABA-containing …

Abnormalities of the anterior cingulate cortex have previously been described in schizophrenia,
major depressive disorder and bipolar disorder. In this study 2‐DE was performed …

Background: Brain imaging studies suggest that volume reductions and compromised white
matter integrity occur in schizophrenia and bipolar disorder (BD). However, the cellular …

Recent studies have provided evidence for a deficit of GABA-containing interneurons in the
frontal cortex in schizophrenia. That this deficit might be brought about during early foetal or …

Objectives: Cholesterol forms an integral part of cell membranes and is a major component
of myelin. Furthermore, cholesterol also plays a vital role in the development, function and …

Deficits in a variety of different neurochemical species are consistent with a loss of cortical γ-aminobutyric
acid (GABA)ergic interneurons in schizophrenia. As well as neurochemical …

Astrocyte dysregulation has been implicated in the pathophysiology of schizophrenia (SCZ)
and bipolar disorder (BPD), however the exact nature of astrocytic alterations remains to be …

The mammalian hippocampus continues to generate new neurons throughout life. The
function of adult-generated neurons remains controversial, but adult neurogenesis in the …

… Author links open overlay panel Clare L. Beasley a , Andrew J. Dwork b c d , Gorazd Rosoklija
b c e , J. John Mann b c , Branislav Mancevski b c , Zlatko Jakovski f , Natasa Davceva f , …