BACKGROUND: Childhood maltreatment represents a strong risk factor for the development
of depression and posttraumatic stress disorder (PTSD) in later life. In the present study, we …

The neuro-anatomical substrates of major depressive disorder (MDD) are still not well
understood, despite many neuroimaging studies over the past few decades. Here we present the …

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …

Major depression has been repeatedly associated with amygdala hyper‐responsiveness to
negative (but not positive) facial expressions at early, automatic stages of emotion …

Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …

Importance The structural abnormalities in the brain that accurately differentiate unipolar
depression (UD) and bipolar depression (BD) remain unidentified. Objectives First, to …

Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research has …

Importance Identifying neurobiological differences between patients with major depressive
disorder (MDD) and healthy individuals has been a mainstay of clinical neuroscience for …

Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent, …