The neuropathological correlates of encephalopathy and autonomic dysfuction in septic shock
are unclear. We performed post mortem analysis of 5 brain areas susceptible to ischemia …

The pathogenesis of cerebral infection after Cryptococcus neoformans fungemia in outbred
mice was investigated. Confocal microscopy and cultures on ficoll-hypaque gradient–…

Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA)
are unusual vasculopathies generally regarded as unrelated disorders. A few case reports …

Background Understanding of sepsis-induced brain dysfunction remains poor, and relies
mainly on data from animals or post-mortem studies in patients. The current study provided …

Early HIV‐1 invasion of the central nervous system has been demonstrated by many
cerebrospinal fluid studies; however, most HIV‐1 carriers remain neurologically unimpaired during …

We examined 11 brains of human immunodeficiency virus (HIV) seropositive cases who died
from unnatural causes (10 intravenous drug abusers who died from heroin overdose and 1 …

… Sharshar, Tarek MD; Carlier, Robert MD; Blanchard, Anne MD, PhD; Feydy, Antoine MD;
Gray, Françoise MD, PhD; Paillard, Michel MD, PhD; Raphael, Jean-Claude MD; Gajdos …

There is overwhelming evidence that invasion of the central nervous system (CNS) by HIV-1
takes place at an early stage of the infection. It has been demonstrated that HIV-1 DNA is …

Highly active antiretroviral treatment (HAART), which has been available for most AIDS
patients in France since 1996, has resulted in a dramatic improvement of the progression of the …

Beta-site APP cleaving enzyme 1 (BACE1) is the rate limiting enzyme for accumulation of
amyloid β (Aβ)-peptide in the brain in Alzheimer's disease (AD). Oxidative stress (OS) that …