Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible
rewards that involve the striatal dopaminergic system. Using the neurochemical specificity of […

10.7554/eLife.08440.001 We mapped the distribution of atrophy in Parkinson's disease (PD)
using magnetic resonance imaging (MRI) and clinical data from 232 PD patients and 117 …

The extent to which we learn from positive and negative outcomes of decisions is modulated
by the neurotransmitter dopamine. Dopamine neurons burst fire in response to unexpected …

10.7554/eLife.26653.001 We investigated the anatomical and functional organization of the
human substantia nigra (SN) using diffusion and functional MRI data from the Human …

Drug-related cues are potent triggers for relapse in people with cocaine dependence. Dopamine
(DA) release within a limbic network of striatum, amygdala and hippocampus has been …

It is becoming increasingly clear that brain network organization shapes the course and
expression of neurodegenerative diseases. Parkinson disease (PD) is marked by progressive …

Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations
that override self-control of food intake. We tested this hypothesis by measuring circulating …

Patient motion during positron emission tomography scanning can affect the accuracy of the
data analysis in two ways: 1) movement occurring during emission data acquisition alters …

Cocaine self-administration decreases type 5 metabotropic glutamate receptor (mGluR5)
tissue concentrations in laboratory rats during early abstinence. These changes are thought to …

Background: Accumulating evidence indicates that drug-related cues can induce dopamine
(DA) release in the striatum of substance abusers. Whether these same cues provoke DA …