Depression is a group of brain disorders with varied origins, complex genetics and obscure
neurobiology. Definitions of clinical phenotypes are not rooted in their neurobiology, and …

Major depressive disorder (MDD) is common and moderately heritable. Recurrence and
early age at onset characterize cases with the greatest familial risk. Major depressive …

Studying the genetics of mood disorders has never been more exciting. We have moved
rapidly from establishing the genetic basis of depression to asking questions about how …

Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

In a number of human diseases, including depression, interactions between genetic and
environmental factors have been identified in the absence of direct genotype-disorder …

BackgroundIt has been well established that both genes and non-shared environment
contribute substantially to the underlying aetiology of major depressive disorder (MDD). A …

The genetic dissection of major depressive disorder (MDD) ranks as one of the success
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …

Major depressive disorder (MDD) is a common and highly heterogeneous psychiatric
disorder encompassing a spectrum of symptoms involving deficits to a range of cognitive …

Major depression is a common disorder, accounting for more disability than any other
disorder worldwide. The rates of major depression in the United States rose markedly in the …

In spite of promising preclinical results there is a decreasing number of new registered
medications in major depression. The main reason behind this fact is the lack of confirmation …