Objectives: To inform clinicians about the types of seizures that can be induced by clozapine
and to provide recommendations for treatment. Methods: We identified articles on clozapine-…

Background Treatment‐resistant depression (TRD) is a debilitating chronic mental illness
that confers increased morbidity and mortality, decreases the quality of life, impairs …

Primary polydipsia, excessive fluid intake without medical cause, is present in over 20% of
seriously and persistently ill psychiatric inpatients. The long-term effects of primary polydipsia …

In patients allocated blindly and randomly to receive bitemporal, right unilateral, or bifrontal
electroconvulsive therapy, seizure length, electrophysiologic characteristics (dynamic …

Objective: To propose a protocol for minimizing medical complications associated with the
use of cyproterone, medroxyprogesterone, and depot leuprolide to treat paraphilia. Method …

OBJECTIVE To raise awareness of risk factors for, and symptoms of, lithium intoxication.
QUALITY OF EVIDENCE The literature was searched via MEDLINE from January 1970 to …

Background Following several landmark rulings and increasing public support for physician-assisted
death, in 2016, Canada became one of a handful of countries legalising medical …

Methods We contacted all 1273 registered health care institutions in Canada and invited the
175 centers identified as providing ECT to complete a comprehensive questionnaire. To …

Primary polydipsia, excessive drinking without known medical cause, is especially
associated with a diagnosis of schizophrenia. We used animal models of schizophrenia-like …

A study was conducted to assess the validity of nocturnal penile tumescence (NPT) as a
means of distinguishing between psychogenic and organic erectile failure (impotence). On the …