The mediodorsal nucleus of the human thalamus is in a crucial position that allows it to
establish connections with diverse cerebral structures, particularly the prefrontal cortex. The …

Four studies have reported that the mediodorsal nucleus of the thalamus (MD) is smaller
and contains fewer neurons in schizophrenia. The MD is a key node in a circuit proposed to …

Previous neuropathological studies on the mediodorsal thalamic nucleus (MD) in
schizophrenia have yielded conflicting results. While some studies suggested that patients …

Background: The thalamus is a brain region of interest in the study of schizophrenia
because it provides critical input to brain regions such as the prefrontal, cingulate, and …

Objective: To describe structural and biochemical evidence from postmortem brains that
implicates the reciprocal connections between the mediodorsal thalamic nucleus and the …

The mediodorsal nucleus (MD) represents just one piece of a complex relay structure
situated within the brain, called the thalamus. MD is characterized by its robust …

Background The importance of neuronal interactions in development, the cortical
dependence of many thalamic nuclei, and the phenomenon of transsynaptic degeneration …

The main thalamic afferentation of the prefrontal cortex (PFC) originates in the mediodorsal
nucleus (MD). Although it is suggested that this pathway is affected in schizophrenia, there is …

The hypoactivity of dorsolateral prefrontal cortex in schizophrenics is well known. One cause
of this hypoactivity may be defective corticocortical or thalamocortical connections. Recent …

The mediodorsal thalamic nucleus (MD) is the principal relay nucleus for the prefrontal
cortex, a brain region thought to be dysfunctional in schizophrenia. Several, but not all …