Background: Previous magnetic resonance imaging (MRI) studies of patients with major
depressive disorder (MDD) have consistently shown bilateral and unilateral reductions in …

BACKGROUND: Magnetic resonance imaging (MRI) has shown lower hippocampal volume
in major depressive disorder (MDD). Preclinical and postmortem studies show that chronic …

We examined age-related changes in the cerebral white matter. Structural magnetic
resonance images (MRIs) and diffusion tensor images (DTIs) were acquired from 69 healthy …

Several neuropsychiatric disorders involving hippocampal structural changes have been
studied extensively using volumetric magnetic resonance imaging (MRI). These studies have …

… Canadian Institutes of Health Research (CIHR) operating grant MOP111049 (PI – Nikolai
Malykhin) was the source of salary (part only) for research nurse Rawle Carter and MRI …

BACKGROUND: Fronto-limbic dysregulation in major depressive disorder (MDD) may be
influenced by early life stress and antidepressant treatment. The present structural MRI study …

Overactivity of the hypothalamic-pituitary-adrenal (HPA) axis in major depressive disorder (MDD)
is among the most consistently replicated biological findings in psychiatry. Magnetic …

Background Reductions in total hippocampus volume have frequently been reported in MRI
studies in major depressive disorder (MDD), but reports of differences in total amygdala …

The functional role of the hippocampal formation in episodic memory has been studied using
functional magnetic resonance imaging (fMRI) for many years. The hippocampus can be …

Previous diffusion tensor imaging (DTI) studies confirmed the vulnerability of frontal callosal
fibers to normal aging. The present study extended this examination systematically to other …