Gender-specific association between serotonin transporter polymorphisms (5-HTTLPR and rs25531) and neuroticism, anxiety and depression in well-defined healthy …
CC Chang, HA Chang, WH Fang, TC Chang… - Journal of Affective …, 2017 - Elsevier
Background A tri-allelic serotonin transporter promoter polymorphism (5-HTTLPR/rs25531)
more effectively determines the levels of transcriptional efficacy than that with the bi-allelic 5-…
more effectively determines the levels of transcriptional efficacy than that with the bi-allelic 5-…
Attenuated vagally-mediated heart rate variability at rest and in response to postural maneuvers in patients with generalized anxiety disorder
…, JF Shyu, TC Chang, SY Huang, CC Chang - Psychological …, 2020 - cambridge.org
BackgroundAltered heart rate variability (HRV), an index of autonomic nervous system
function, has been reported in generalized anxiety disorder (GAD), but the results have been …
function, has been reported in generalized anxiety disorder (GAD), but the results have been …
Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans
CC Chang, WH Fang, HA Chang, TC Chang… - …, 2017 - Elsevier
Decreased resting vagal (parasympathetic) tone is implicated in the development of stress-related
disorders, including anxiety and depression. Chronic stress elevates the expression …
disorders, including anxiety and depression. Chronic stress elevates the expression …
Age-specific associations among functional COMT Val158Met polymorphism, resting parasympathetic nervous control and generalized anxiety disorder
…, JF Shyu, SY Huang, TC Chang, CC Chang - …, 2019 - Elsevier
The functional Val 158 Met polymorphism (rs4680) of the Catechol-O-Methyltransferase (COMT)
gene has been implicated in generalized anxiety disorder (GAD); however, the …
gene has been implicated in generalized anxiety disorder (GAD); however, the …
[HTML][HTML] Association of neuropeptide Y promoter polymorphism (rs16147) with perceived stress and cardiac vagal outflow in humans
HA Chang, WH Fang, TC Chang, SY Huang… - Scientific Reports, 2016 - nature.com
Neuropeptide Y (NPY) is involved in resilience to stress and higher vagal (parasympathetic)
activity has been associated with greater stress resilience. Thus, we examined whether …
activity has been associated with greater stress resilience. Thus, we examined whether …
BDNF Val⁶⁶Met polymorphism to generalized anxiety disorder pathways: Indirect effects via attenuated parasympathetic stress-relaxation reactivity.
…, SY Huang, TC Chang, CC Chang - Journal of Abnormal …, 2020 - psycnet.apa.org
The valine⁶⁶methionine (Val⁶⁶Met) polymorphism (rs6265) of the brain-derived neurotrophic
factor (BDNF) gene has been shown to influence autonomic arousal pathways, which in …
factor (BDNF) gene has been shown to influence autonomic arousal pathways, which in …
Sex-specific pathways among tri-allelic serotonin transporter polymorphism, trait neuroticism and generalized anxiety disorder
…, FJ Wan, SY Huang, TC Chang, CC Chang - Journal of Psychiatry and …, 2020 - jpn.ca
Background: Neuroticism personality trait is recognized as an important endophenotypic
predictor of generalized anxiety disorder (GAD). Furthermore, endophenotype-based pathway …
predictor of generalized anxiety disorder (GAD). Furthermore, endophenotype-based pathway …
Age-dependent association of polymorphisms in the promoter and 5′-untranslated region of the norepinephrine transporter gene with generalized anxiety disorder
…, FJ Wan, SY Huang, TC Chang, CC Chang - Journal of Affective …, 2020 - Elsevier
Background Norepinephrine transporter (NET), which regulates synaptic norepinephrine for
noradrenergic signaling, is involved in the pathogenesis of anxiety, while expression of the …
noradrenergic signaling, is involved in the pathogenesis of anxiety, while expression of the …
Escitalopram induced thrombocytopenia reversed after shifting to bupropion in a depressive patient.
…, HA Chang, YW Liu, TC Chang… - Australian & New …, 2017 - search.ebscohost.com
The article presents a case study of a 31-year-old physically healthy and drug-naïve
Taiwanese male who received anti-depressants for depressed mood. Topics discussed include …
Taiwanese male who received anti-depressants for depressed mood. Topics discussed include …
Lurasidone associated neutropenia.
S Singh, H Ahmad, AP John - Australian & New Zealand …, 2017 - search.ebscohost.com
The article presents a case study of a 49-year-old white woman who was presented for
review at a community mental health service following remission of a manic episode. Topics …
review at a community mental health service following remission of a manic episode. Topics …
