A 72-year-old man with a longstanding history of bipolar affective disorder type 1 had been
stable on lithium monotherapy of 900 mg/night at a serum level of 0.8 mmol/L for more than …

A 37-year-old male patient had been feeling predominantly depressed and anxious over the
past 15 years. About twice a year, he experienced a self-limited hypomanic episode. He …

Chronic neurotoxicity caused by lithium salts can be reversible or irreversible and may
appear after years of treatment, even at serum levels considered within the usual therapeutic …

DISCUSSION In older patients, in the case of an acute change in mental status, the
hypothesis of subdural hematoma must always be excluded, even if focal neurological …

Objective: Lithium is a principal drug used in the treatment of bipolar disorder (BPD). Due to
its narrow therapeutic index, serum levels need to be monitored regularly. In elderly patients …

A 73-year-old woman with bipolar disorder was stable on lithium. After long-term use of
lithium, she developed chronic renal failure. We stopped her lithium and tried alternatives …

BackgroundInsufficient knowledge on the longitudinal fate of renal function in lithium
patients incited this retrospective study of 149 patients. MethodMedical record review of a …

Some elderly patients on chronic lithium therapy for bipolar disorder and their doctors may
be faced with a therapeutic dilemma over whether or not to continue prescribing/taking …

When prescribing lithium, the risk of toxicity remains a concern. In this study, we examined a
cohort of patients exposed to lithium between 1997 and 2013. The aims of this study were to …

Lithium has been used in clinical practice since the 1970s. This medication is commonly
used to treat and prevent bipolar disorder, but it has a narrow therapeutic index, making …