Psychiatric disorders and leukocyte telomere length: underlying mechanisms linking mental illness with cellular aging
D Lindqvist, ES Epel, SH Mellon, BW Penninx… - Neuroscience & …, 2015 - Elsevier
Many psychiatric illnesses are associated with early mortality and with an increased risk of
developing physical diseases that are more typically seen in the elderly. Moreover, certain …
developing physical diseases that are more typically seen in the elderly. Moreover, certain …
Telomeres and early-life stress: an overview
LH Price, HT Kao, DE Burgers, LL Carpenter… - Biological …, 2013 - Elsevier
The long-term sequelae of adverse early-life experiences have long been a focus in
psychiatry, with a historic neurobiological emphasis on physiological systems that are …
psychiatry, with a historic neurobiological emphasis on physiological systems that are …
Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study
There is increasing interest in discovering mechanisms that mediate the effects of childhood
stress on late-life disease morbidity and mortality. Previous studies have suggested one …
stress on late-life disease morbidity and mortality. Previous studies have suggested one …
The association between psychiatric disorders and telomere length: a meta-analysis involving 14,827 persons
SM Darrow, JE Verhoeven, D Révész… - Psychosomatic …, 2016 - journals.lww.com
Objective This study examined the relationship between leukocyte telomere length (LTL), a
marker of cell aging, and psychiatric disorders in adults compared with controls using meta …
marker of cell aging, and psychiatric disorders in adults compared with controls using meta …
Oxidative stress in anxiety and comorbid disorders
I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …
diseases that often occur together. Oxidative stress has been suggested to contribute to their …
Alterations of mitochondrial DNA copy number and telomere length with early adversity and psychopathology
Background Telomere shortening and alterations of mitochondrial biogenesis are involved
in cellular aging. Childhood adversity is associated with telomere shortening, and several …
in cellular aging. Childhood adversity is associated with telomere shortening, and several …
Childhood exposure to violence and lifelong health: Clinical intervention science and stress-biology research join forces
TE Moffitt - Development and psychopathology, 2013 - cambridge.org
Many young people who are mistreated by an adult, victimized by bullies, criminally
assaulted, or who witness domestic violence react to this violence exposure by developing …
assaulted, or who witness domestic violence react to this violence exposure by developing …
Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls
L Kananen, I Surakka, S Pirkola, J Suvisaari… - PloS one, 2010 - journals.plos.org
Accelerated leukocyte telomere shortening has been previously associated to self-perceived
stress and psychiatric disorders, including schizophrenia and mood disorders. We set out to …
stress and psychiatric disorders, including schizophrenia and mood disorders. We set out to …
Accelerating research on biological aging and mental health: Current challenges and future directions
Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …
even temporarily reversed by biological and non-biological factors. This article focuses on …
Systemic biomarkers of accelerated aging in schizophrenia: a critical review and future directions
TT Nguyen, LT Eyler, DV Jeste - Schizophrenia bulletin, 2018 - academic.oup.com
Background: Schizophrenia is associated with increased physical morbidity and early
mortality, suggesting that the aging process may be accelerated in schizophrenia. However …
mortality, suggesting that the aging process may be accelerated in schizophrenia. However …