Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia. The
revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and …

Dopamine is an important neurotransmitter that plays a key role in neuropsychiatric illness.
Sex differences in dopaminergic signaling have been acknowledged for decades and have …

Rates of obesity are higher than normal across a range of psychiatric disorders, including
major depressive disorder, bipolar disorder, schizophrenia and anxiety disorders. While the …

Background: The dopamine D2 receptor is the common target for antipsychotics, and the
antipsychotic clinical doses correlate with their affinities for this receptor. Antipsychotics …

Many books in medical literature have become so well-established over the years that they
are known by the names of the founding author (s) or editor (s). Notable examples are …

The antipsychotic effectiveness of chlorpromazine and haloperidol started a search for their
therapeutic targets. The antipsychotic receptor target turned out to be a dopamine receptor …

The pharmacological modification of dopamine transmission has long been employed as a
therapeutic tool in the treatment of many mental health disorders. However, as many of the …

Numerous genetic linkage and association studies implicate members of the Neuregulin-
ErbB receptor (NRG-ErbB) signaling pathway as schizophrenia “at risk” genes. An emphasis …

Psychosis is a symptom complex that may include hallucinations, delusions, disorders of
thought, and disorganized speech or behavior. Acute psychosis is primary if it is …

Psychiatric and neurodegenerative disorders, including intellectual disability, autism
spectrum disorders (ASD), schizophrenia (SZ), and Alzheimer's disease, pose an immense …