Introduction Antipsychotic (AP) safety has been widely investigated. However, mechanisms
underlying AP-associated pneumonia are not well-defined. Aim The aim of this study was to …

Objective: To describe 3 cases of clozapine toxicity associated with infectious and/or
inflammatory processes. Case Summaries: Three patients stable on clozapine therapy prior …

This case study compares two different clinical outcomes for a patient with a long-standing
psychotic disorder prescribed clozapine on two occasions. During the first trial, clozapine …

To the Editors: Clozapine, an atypical antipsychotic, has been demonstrated to be superior
for the treatment of refractory schizophrenia compared with other antipsychotics. 1 Despite …

Clozapine is often the drug of choice within patients suffering from treatment-resistant
paranoid schizophrenia. It has a complex side effects profile which includes potentially fatal …

Discussion The “knee-buckling” episodes with clozapine in our case is similar to previous
reports of cataplexy-like phenomenon or “leg folding” phenomena with clozapine. 1 Indeed …

DISCUSSION We describe a case of clozapine-associated necrotizing pneumonia in an
immunocompetent patient. Clozapine-associated pneumonia may be underrecognized; …

To the Editors: Although schizophrenia is one of the most disabling psychiatric conditions
affecting young adults, the prevalence and impact in the elderly are also considerable. 1 …

DISCUSSION We describe the oldest patient and the lowest dose in the literature with
clozapine-associated negative myoclonus. Clozapine-associated negative myoclonus has …

Objective: To describe lemborexant for the treatment of insomnia (DSM-5) in adults using
number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped …