Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants

CB Eap, G Gründer, P Baumann… - The World Journal of …, 2021 - Taylor & Francis
Objectives: More than 40 drugs are available to treat affective disorders. Individual selection
of the optimal drug and dose is required to attain the highest possible efficacy and …

[BOOK][B] Nurturing natures: Attachment and children's emotional, sociocultural and brain development

G Music - 2016 - taylorfrancis.com
This new edition of the bestselling text, Nurturing Natures, provides an indispensable
synthesis of the latest scientific knowledge about children's emotional development …

Catecholaminergic regulation of learning rate in a dynamic environment

M Jepma, PR Murphy, MR Nassar… - PLoS computational …, 2016 - journals.plos.org
Adaptive behavior in a changing world requires flexibly adapting one's rate of learning to the
rate of environmental change. Recent studies have examined the computational …

Noradrenergic and cholinergic modulation of belief updating

M Jepma, SBRE Brown, PR Murphy… - Journal of cognitive …, 2018 - direct.mit.edu
To make optimal predictions in a dynamic environment, the impact of new observations on
existing beliefs—that is, the learning rate—should be guided by ongoing estimates of …

The effect of sertraline on emotional processing: Secondary analyses of the PANDA randomised controlled trial

N Ahmed, JK Bone, G Lewis, N Freemantle… - Psychological …, 2022 - cambridge.org
BackgroundAccording to the cognitive neuropsychological model, antidepressants reduce
symptoms of depression and anxiety by increasing positive relative to negative information …

Are COMT Val158Met (rs4680), DRD2 TaqIA (rs1800497), and BDNF Val66Met (rs6265) polymorphisms associated with executive functions performance at rest and …

T Frois, LO Faria, RP de Souza, AE da Silva Cunha… - Physiology & …, 2022 - Elsevier
Executive functions (EFs) encompass a wide array of cognitive processes, which appear to
be influenced by genetic variants of the COMT, DRD2/ANKK1, and BDNF polymorphisms …

Catechol-O-methyltransferase activity does not influence emotional processing in men

MAG Martens, N Dalton, J Scaife… - Journal of …, 2022 - journals.sagepub.com
Background: Catechol-O-methyltransferase (COMT) regulates cortical dopaminergic
transmission and prefrontal-dependent cognitive function. However, its role in other …

The association between sleep-wake ratio and overnight picture recognition is moderated by BDNF genotype

R Halonen, L Kuula, J Lahti, K Räikkönen… - … of Learning and …, 2021 - Elsevier
A wealth of studies supports the role of sleep in memory performance. Experimentally
controlled studies indicate that prolonged wake after memory encoding is detrimental for …

Genetics of human memory functions in healthy cohorts

A Papassotiropoulos, DJF de Quervain - Current Opinion in Behavioral …, 2015 - Elsevier
Highlights•Human genetic research contributes to the understanding of memory-related
molecular processes.•Here we review candidate gene and genome-wide association …

[PDF][PDF] Sleep and its oscillatory characteristics in overnight learning-what is the role of plasticity genes BDNF and COMT?

R Halonen - 2022 - core.ac.uk
Sleep is crucial for human health and function. Decades of research have accumulated our
understanding on the influence of sleep–or the lack of it–on different domains such as …