Epilepsy is one of the most common neurological disorders in humans with a prevalence of
1% and a lifetime incidence of 3%. Several genes have been identified in rare autosomal …

Generalized epilepsy with febrile seizures plus type 2 (GEFS+ 2, MIM 604233) is an autosomal
dominant disorder characterized by febrile seizures in children and afebrile seizures in …

We identified 15q13.3 microdeletions encompassing the CHRNA7 gene in 12 of 1,223
individuals with idiopathic generalized epilepsy (IGE), which were not detected in 3,699 controls (…

OBJECTIVE: The understanding of suicidal behavior is incomplete. The stress-diathesis model
suggests that a deficit in serotonergic projections to the orbitofrontal cortex is involved in …

Humans have an individual profile of the electroencephalographic power spectra at the 8 to
16Hz frequency during non–rapid eye movement sleep that is stable over time and resistant …

Progressive myoclonus epilepsy of the Unverricht–Lundborg type (EPM1; MIM 254800) is
an autosomal recessive disorder with onset between 6 and 13 years followed by variable …

Downregulation of brain-derived neurotrophic factor (BDNF) gene expression with
corresponding increased methylation at specific promoters has been associated with stressful …

The genetic variation in spontaneous rhythmic electroencephalographic (EEG) activity was
assessed by the quantitative analysis of the EEG in six inbred mice strains. Mean spectral …

Decision-making impairment has been linked to orbitofrontal cortex lesions and to different
disorders including substance abuse, aggression and suicidal behavior. Understanding the …

Objectives. Transmission of parental post-traumatic stress disorder (PTSD) to offspring might
be explained by transmission of epigenetic processes such as methylation status of the …