User profiles for Alice S. Wong

Alice ST Wong

Professor, University of Hong Kong
Verified email at hku.hk
Cited by 10444

A longitudinal study of stress‐induced hippocampal volume changes in mice that are susceptible or resilient to chronic social defeat

YC Tse, I Montoya, AS Wong, A Mathieu… - …, 2014 - Wiley Online Library
Hippocampal shrinkage is a commonly found neuroanatomical change in stress‐related
mood disorders such as depression and post‐traumatic stress disorders (PTSD). Since the …

Negative memory engrams in the hippocampus enhance the susceptibility to chronic social defeat stress

…, V Wong, AS Wong, TP Wong - Journal of …, 2019 - Soc Neuroscience
The hippocampus has been highly implicated in depression symptoms. Recent findings
suggest that the expression and susceptibility of depression symptoms are related to the …

[HTML][HTML] Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus

YC Tse, RC Bagot, JA Hutter, AS Wong, TP Wong - PLoS One, 2011 - journals.plos.org
Stress exerts a profound impact on learning and memory, in part, through the actions of
adrenal corticosterone (CORT) on synaptic plasticity, a cellular model of learning and memory. …

Single-cell EMT-related transcriptional analysis revealed intra-cluster heterogeneity of tumor cell clusters in epithelial ovarian cancer ascites

T Kan, W Wang, PP Ip, S Zhou, AS Wong, X Wang… - Oncogene, 2020 - nature.com
Malignant ascites of epithelial ovarian cancer is a metastatic tumor microenvironment in which
large amounts of disseminated single cells (DSCs) and disseminated tumor cell clusters (…

Maternal care influences hippocampal N-methyl-D-aspartate receptor function and dynamic regulation by corticosterone in adulthood

…, HB Nguyen, AS Wong, MJ Meaney, TP Wong - Biological …, 2012 - Elsevier
BACKGROUND: Variations in maternal care in the rat associate with robust differences in
hippocampal development and synaptic plasticity in the offspring. Maternal care also …

An evaluation of HPLC for the screening and quantitation of benzodiazepines and acetaminophen in post mortem blood

AS Wong - Journal of Analytical Toxicology, 1983 - academic.oup.com
High performance liquid chromatographic (HPLC) methods have been developed for the
analysis of benzodiazepines, some of their metabolites and for acetaminophen in post mortem …

SIRT6 induces EMT and promotes cancer cell invasion and migration in prostate cancer

Q Xie, AS Wong, W Xia - Cancer Research, 2014 - hub.hku.hk
Prostate cancer (PCa) is the most common cancer and the second leading cause of cancer
related death in males in the developed countries. One of the major clinical challenges is the …

The 43rd Annual Meeting of the Canadian College of Neuropsychopharmacology, November 4, 2021Role of histone 3.3 lysine 27 methylation in conferring enduring …

…, X Long, TR Zhang, AS Wong, BCM Fung, TP Wong… - 2022 - jpn.ca
Background: Depression is a prevalent psychiatric disorder characterized by heterogeneous
symptoms that can last a lifetime and remain even after several courses of antidepressant …

Transcriptional downregulation of microRNA 199a-1 in the tumor microenvironment confers chemoresistance and stemness in ovarian cancer cells

AA Hassan, Z Yang, HC Shum, HC Lai, AS Wong - Cancer Research, 2020 - AACR
The tumor microenvironment is actively involved in cancer progression and is becoming an
attractive therapeutic target. It is increasingly clear that both biotic and abiotic factors in the …

Nuclear localization of p70 S6 kinase in ovarian cancer

J Zhou, SK To, AS Wong - Cancer Research, 2018 - AACR
… TO, Alice S. WONG. Nuclear localization of p70 S6 kinase in ovarian cancer [abstract]. In:
Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 …