Intracranial and subcortical volumes in adolescents with early‐onset psychosis: A multisite mega‐analysis from the ENIGMA consortium

…, S Frangou, BI Goldstein, A Grigorian… - Human brain …, 2022 - Wiley Online Library
Early‐onset psychosis disorders are serious mental disorders arising before the age of 18
years. Here, we investigate the largest neuroimaging dataset, to date, of patients with early‐…

Elevated lipids are associated with reduced regional brain structure in youth with bipolar disorder

KG Kennedy, AH Islam, A Grigorian… - Acta Psychiatrica …, 2021 - Wiley Online Library
Anahit GrigorianAnahit Grigorian … Islam and Anahit Grigorian provided support in
neuroimaging. Lisa Fiksenbaum provided statistical support. Rachel HB Mitchell, Brian W. …

Normal cerebral oxygen consumption despite elevated cerebral blood flow in adolescents with bipolar disorder: putative neuroimaging evidence of anomalous energy …

S Karthikeyan, L Fiksenbaum, A Grigorian, H Lu… - Frontiers in …, 2019 - frontiersin.org
Background: Regional cerebral blood flow (CBF) is reportedly altered in both adolescents
and adults with bipolar disorder (BD). Whether these CBF differences are part of an overall …

[HTML][HTML] Cerebral Blood Flow and Core Mood Symptoms in Youth Bipolar Disorder: Evidence for Region–Symptom Specificity

MK Dimick, S Toma, BJ MacIntosh, A Grigorian… - Journal of the American …, 2022 - Elsevier
Objective Building on prior findings in adults, this study investigated regional cerebral blood
flow (CBF) in relation to DSM-5 criterion A symptoms of depression and mania in youth with …

[HTML][HTML] Measuring brain temperature in youth bipolar disorder using a novel magnetic resonance imaging approach: a proof-of-concept study

Y Zou, C Heyn, A Grigorian, F Tam… - Current …, 2023 - ncbi.nlm.nih.gov
Background There is evidence of alterations in mitochondrial energy metabolism and cerebral
blood flow (CBF) in adults and youth with bipolar disorder (BD). Brain thermoregulation is …

Association of blood pressure with brain structure in youth with and without bipolar disorder

KG Kennedy, A Grigorian, RHB Mitchell… - Journal of Affective …, 2022 - Elsevier
Background We previously found that blood pressure (BP) is elevated, and associated with
poorer neurocognition, in youth with bipolar disorder (BD). While higher BP is associated …

Neurovascular correlates of retinal microvascular caliber in adolescent bipolar disorder

M Mio, A Grigorian, Y Zou, MK Dimick, B Selkirk… - Journal of Affective …, 2023 - Elsevier
Background The connection between vascular and brain metrics is well-studied in older
adults, but neglected in youth and in psychiatric populations at increased cardiovascular risk. …

Antioxidative defense genes and brain structure in youth bipolar disorder

Y Zou, KG Kennedy, A Grigorian… - International Journal …, 2022 - academic.oup.com
Background Oxidative stress is implicated in the neuropathology of bipolar disorder (BD).
We investigated the association of single-nucleotide polymorphisms (SNPs) in the …

Differential association of antioxidative defense genes with white matter integrity in youth bipolar disorder

Y Zou, A Grigorian, KG Kennedy, CC Zai… - Translational …, 2022 - nature.com
Oxidative stress is associated with white matter diffusion metrics in adults with bipolar disorder
(BD). We examined the association of single-nucleotide polymorphisms in the oxidative …

Elevated C-reactive protein among symptomatic youth with bipolar disorder

Y Zou, A Grigorian, S Karthikeyan… - Journal of …, 2022 - journals.sagepub.com
Rationale and Objectives: Increased levels of high-sensitivity C-reactive protein (CRP) are
associated with mood symptoms in adults with bipolar disorder (BD). The few studies on this …