User profiles for Andrea Mechelli

Professor Andrea Mechelli

Institute of Psychiatry, Psychology & Neuroscience
Verified email at kcl.ac.uk
Cited by 28312

Voxel-based morphometry of the human brain: methods and applications

A Mechelli, CJ Price, KJ Friston… - Current Medical …, 2005 - ingentaconnect.com
In recent years, a whole-brain unbiased objective technique, known as voxel-based morphometry
(VBM), has been developed to characterise brain differences in vivo using structural …

[HTML][HTML] Structural plasticity in the bilingual brain

A Mechelli, JT Crinion, U Noppeney, J O'Doherty… - Nature, 2004 - nature.com
Humans have a unique ability to learn more than one language — a skill that is thought to
be mediated by functional (rather than structural) plastic changes in the brain 1 . Here we …

Using support vector machine to identify imaging biomarkers of neurological and psychiatric disease: a critical review

…, AF Marquand, G Sartori, A Mechelli - Neuroscience & …, 2012 - Elsevier
Standard univariate analysis of neuroimaging data has revealed a host of neuroanatomical
and functional differences between healthy individuals and patients suffering a wide range of …

Comparing dynamic causal models

WD Penny, KE Stephan, A Mechelli, KJ Friston - Neuroimage, 2004 - Elsevier
This article describes the use of Bayes factors for comparing dynamic causal models (DCMs).
DCMs are used to make inferences about effective connectivity from functional magnetic …

[HTML][HTML] Brain charts for the human lifespan

…, B Mazoyer, P McGuire, MJ Meaney, A Mechelli… - Nature, 2022 - nature.com
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

Nonlinear responses in fMRI: the Balloon model, Volterra kernels, and other hemodynamics

KJ Friston, A Mechelli, R Turner, CJ Price - NeuroImage, 2000 - Elsevier
There is a growing appreciation of the importance of nonlinearities in evoked responses in
fMRI, particularly with the advent of event-related fMRI. These nonlinearities are commonly …

The hubs of the human connectome are generally implicated in the anatomy of brain disorders

NA Crossley, A Mechelli, J Scott, F Carletti, PT Fox… - Brain, 2014 - academic.oup.com
Brain networks or ‘connectomes’ include a minority of highly connected hub nodes that are
functionally valuable, because their topological centrality supports integrative processing and …

Dysconnectivity in schizophrenia: where are we now?

…, P Allen, S Benetti, P McGuire, A Mechelli - Neuroscience & …, 2011 - Elsevier
The disconnection hypothesis suggests that the core symptoms of schizophrenia (SZ) are
related to aberrant, or ‘dys-’, connectivity between distinct brain regions. A proliferation of …

Structural covariance in the human cortex

A Mechelli, KJ Friston, RS Frackowiak… - Journal of …, 2005 - Soc Neuroscience
The morphology of the human cortex varies remarkably across individuals, regardless of
overall brain size. It is currently unclear whether related cortical regions covary in gray matter …

[HTML][HTML] Using deep learning to investigate the neuroimaging correlates of psychiatric and neurological disorders: Methods and applications

S Vieira, WHL Pinaya, A Mechelli - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Deep learning (DL) is a family of machine learning methods that has gained considerable
attention in the scientific community, breaking benchmark records in areas such as speech …