Background. A dysfunctional differentiation between self-relevant and irrelevant information
may affect the perception of environmental stimuli as abnormally salient. The aberrant …

The striatum is known to play a key role in reinforcement learning, specifically in the encoding
of teaching signals such as reward prediction errors (RPEs). It has been proposed that …

Theoretical and animal work has proposed that prefrontal cortex (PFC) glutamate inhibits
dopaminergic inputs to the ventral striatum (VS) indirectly, whereas direct VS glutamatergic …

Pyrin is a cytosolic immune sensor that nucleates an inflammasome in response to inhibition
of RhoA by bacterial virulence factors, triggering the release of inflammatory cytokines, …

Introduction Autoinflammatory diseases (AID) are rare diseases presenting with episodes of
sterile inflammation. These involve multiple organs and can cause both acute organ …

Objectives The aim of this study was to assess the safety and efficacy of long-term low-dose
glucocorticoids (GCs) in RA. Methods A protocolised systematic review and meta-analysis (…

Dopamine dysfunction is a mainstay of theories aimed to explain the neurobiological
correlates of schizophrenia symptoms, particularly positive symptoms such as delusions and …

Dysfunctional emotion processing in patients suffering from schizophrenia is a prominent
clinical feature of great importance for social functioning and subjective well-being. The …

In the present study, we explored possible alterations in the default mode network (DMN)
and its functional connectivity in 41 schizophrenia patients and 42 age-matched healthy …

Getting access to specialists for autoinflammatory diseases (AID) can be challenging. Therefore,
an increasing number of patients and healthcare professionals are seeking information …