Cognitive impairment is a core feature of schizophrenia which precedes the onset of full
psychotic symptoms, even in the ultra-high-risk stage (UHR). Polygenic risk scores (PRS) can be …

Methods We searched PubMed, and Embase databases and classified the articles
depending on the epigenetic mechanisms (DNA methylation, histone modifications and non-coding …

Brain anomalies are frequently found in early psychoses. Although they may remain
undetected for many years, their interpretation is critical for differential diagnosis. In secondary …

Psychosis frequently occurs during adolescence and young adulthood, possibly as a result
of gene-environment interactions, mediated by epigenetic mechanisms such as DNA …

Introduction The emergence of psychosis in at-risk individuals results from interactions between
genetic vulnerability and environmental factors, possibly involving dysregulation of the …

Background Quantitative electroencephalography (EEG) analysis offers the opportunity to
study high-level cognitive processes across psychiatric disorders. In particular, EEG …

Introduction Prader–Willi Syndrome (PWS) is a rare genetic condition, which affects one in
25,000 births and results in various phenotypes. It leads to a wide range of metabolic and …

Down syndrome (DS) is one of the most frequent genetic disorders and represents the first
cause of intellectual disability of genetic origin. While the majority of patients with DS follow a …

Psychoanalysis' long-standing influence in French psychiatry has faced severe criticism for
the past 20 years. From media coverage feeding this fiery dispute, to a health minister …

The seven human 14-3-3 proteins are encoded by the YWHA-gene family. They are expressed
in the brain where they play multiple roles including the modulation of synaptic plasticity …