With the advancement of novel techniques in drug discovery, various approaches have
been used in the structure based drug designing. One of the most important strategies is …

The patterns of axonal collateralization of nucleus accumbens (Acb) projection neurons were
investigated in the rat by means of single‐axon tracing techniques using the anterograde …

The ventral pallidum (VP) is a key component of the cortico-basal ganglia circuits that process
motivational and emotional information, and also a crucial site for reward. Although the …

P-glycoprotein (P-gp) is well known to cause multidrug resistance (MDR) in cancer cells.
This MDR leads to cancer recurrence which is a major obstacle in cancer treatment. High P-gp …

Drug discovery and development are critical processes that enable the treatment of wide
variety of health-related problems. These are time-consuming, tedious, complicated, and costly …

After the development of next-generation sequencing techniques, protein sequences are
abundantly available. Determining the functional characteristics of these proteins is costly and …

Protein function prediction is a major challenge in the field of bioinformatics which aims at
predicting the functions performed by a known protein. Many protein data forms like protein …

Genetic microdeletion at the 22q11 locus is associated with very high risk for schizophrenia.
The 22q11.2 microdeletion (Df(h22q11)/+) mouse model shows cognitive deficits observed …

Despite the vast amount of research on schizophrenia and depression in the past two decades,
there have been few innovative drugs to treat these disorders. Precompetitive research …

Her brother in Joharabad, Punjab, set Ghazala on fire, on 6 January 1999. According to
reports, she was murdered because her family suspected she was having an ‘illicit’relationship …