Although it is being successfully implemented for exploration of the genome, discovery
science has eluded the functional neuroimaging community. The core challenge remains the …

Working memory refers to the short-term retention of information that is no longer accessible
in the environment, and the manipulation of this information, for subsequent use in guiding …

… Initial work on this project formed a portion of Bart Rypma's master's thesis. The data were
presented at the annual meeting of the Psychonomic Society, Atlanta, GA, November, 1989.…

Using an event-related functional MRI design, we explored the relative roles of dorsal and
ventral prefrontal cortex (PFC) regions during specific components (Encoding, Delay, …

Brain imaging studies have suggested a critical role for prefrontal cortex in working memory
(WM) tasks that require both maintainenance and manipulation of information over time in …

Working memory (WM), the process by which information is coded into memory, actively
maintained and subsequently retrieved, declines with age. To test the hypothesis that age-…

The use of functional neuroimaging to test hypotheses regarding age-related changes in the
neural substrates of cognitive processes relies on assumptions regarding the coupling of …

Brain imaging and behavioral studies of working memory (WM) converge to suggest that the
ventrolateral prefrontal cortex (PFC) mediates a capacity-limited storage buffer and that the …

Since its inception, experimental psychology has sought to account for individual differences
in human performance. Some neuroimaging research, involving complex behavioral …

A number of spatial reasoning problems can be solved by performing an imagined
transformation of one’s egocentric perspective. A series of experiments were carried out to …