User profiles for Benjamin García

Ben Garcia

- Verified email at mail.med.upenn.edu - Cited by 52752

Benjamin Garcia Garcia

- Verified email at carm.es - Cited by 4092

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

…, M Hergueta-Redondo, C Williams, G García-Santos… - Nature medicine, 2012 - nature.com
Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function
of melanoma-derived exosomes in the formation of primary tumors and metastases in …

Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation

…, BS Tseng, HL Dormann, BM Ueberheide, BA Garcia… - Nature, 2005 - nature.com
Tri-methylation of histone H3 lysine 9 is important for recruiting heterochromatin protein 1 (HP1)
to discrete regions of the genome, thereby regulating gene expression, chromatin …

[PDF][PDF] Extracellular vesicle and particle biomarkers define multiple human cancers

…, H Wang, A Harris, LM Schaeffer, G García-Santos… - Cell, 2020 - cell.com
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection.
We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in …

Optimal proportions of crabs and fish in diet for common octopus (Octopus vulgaris) ongrowing

BG García, JC Valverde - Aquaculture, 2006 - Elsevier
Although the ongrowing of Octopus vulgaris shows great economic potential, to date, no
commercially available diet exists so that trawled fish species of low economic value, which …

Tumour exosome integrins determine organotropic metastasis

…, V Muller, K Pantel, AJ Minn, MJ Bissell, BA Garcia… - Nature, 2015 - nature.com
Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …

Growth, feed efficiency and condition of common octopus (Octopus vulgaris) fed on two formulated moist diets

…, MD Hernández, F Aguado-Giménez, BG García - Aquaculture, 2008 - Elsevier
In the present study, the growth, feed efficiency and condition of Octopus vulgaris (0.58 to
1.02 kg; 17 to 21 C) fed two formulated moist diets based on fish and prawn mixed with …

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

…, F Cordero, S Lin, LA Banaszynski, BA Garcia… - Science, 2013 - science.org
Sequencing of pediatric gliomas has identified missense mutations Lys27Met (K27M) and
Gly34Arg/Val (G34R/V) in genes encoding histone H3.3 (H3F3A) and H3.1 (HIST3H1B). We …

First light with RATIR: an automated 6-band optical/NIR imaging camera

…, A Córdova, A Farah, B García… - Ground-based and …, 2012 - spiedigitallibrary.org
The Reionization and Transients InfraRed camera (RATIR) is a simultaneous optical/NIR
multi-band imaging camera which is 100% time-dedicated to the followup of Gamma-ray Bursts…

Cytoplasmic chromatin triggers inflammation in senescence and cancer

…, JT Seykora, SE Millar, KH Kaestner, BA Garcia… - Nature, 2017 - nature.com
Chromatin is traditionally viewed as a nuclear entity that regulates gene expression and
silencing 1 , 2 , 3 . However, we recently discovered the presence of cytoplasmic chromatin …

How many human proteoforms are there?

…, BF Cravatt, C Fenselau, BA Garcia… - Nature chemical …, 2018 - nature.com
Despite decades of accumulated knowledge about proteins and their post-translational
modifications (PTMs), numerous questions remain regarding their molecular composition and …