An anatomical parcellation of the spatially normalized single-subject high-resolution T1 volume
provided by the Montreal Neurological Institute (MNI) (DL Collins et al., 1998, Trans. Med…

Uptill now, the study of regional gray matter atrophy in Alzheimer's disease (AD) has been
assessed with regions of interest, but this method is time-consuming, observer dependent, …

Capturing the dynamics of gray matter (GM) atrophy in relation to the conversion from mild
cognitive impairment (MCI) to clinically probable Alzheimer's disease (AD) would be of …

With age, the brain undergoes both structural and functional alterations, probably resulting
in reported cognitive declines. Relatively few investigations have sought to identify those …

In early Alzheimer's disease (AD), the hippocampal region is the area most severely affected
by cellular and structural alterations, yet glucose hypometabolism predominates in the …

Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described
hallmarks of Alzheimer's disease, but their relationships are poorly understood. The …

The aim of this study was to determine the neuronal basis for memory impairment in
Alzheimer's disease by taking advantage of the clinical and metabolic heterogeneity of this …

More educated elders are less susceptible to age-related or pathological cognitive changes.
We aimed at providing a comprehensive contribution to the neural mechanism underlying …

The present study aims to unravel, in the same study, both morphological and functional
specific substrates of encoding versus retrieval deficits in patients with amnestic mild cognitive …

Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral
amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and …