User profiles for Bruno Giros

Bruno Giros

Douglas Research Institute - McGill University
Verified email at mcgill.ca
Cited by 33822

Molecular characterization of the dopamine transporter

B Giros, MG Caron - Trends in pharmacological sciences, 1993 - cell.com
~ eur~ trffns~~ jssjo~, which represents chemical signalting betzueen neurons, usually fakes
place af highly differenfiated anatomical sfructures catted synapses. To fulfill both the time …

The dopamine transporter: a crucial component regulating dopamine transmission

M Jaber, S Jones, B Giros… - … disorders: official journal …, 1997 - Wiley Online Library
The dopamine system is implicated in the control of locomotion, cognition, and endocrine
function, The relative contribution of the various dopamine‐related components is not well …

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

P Sokoloff, B Giros, MP Martres, ML Bouthenet… - Nature, 1990 - nature.com
A dopamine receptor has been characterized which differs in its pharmacology and
signalling system from the D 1 or D 2 receptor and represents both an autoreceptor and a …

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

B Giros, M Jaber, SR Jones, RM Wightman, MG Caron - Nature, 1996 - nature.com
Disruption of the mouse dopamine transporter gene results in spontaneous hyperlocomotion
despite major adaptive changes, such as decreases in neurotransmitter and receptor levels…

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

…, C Colineaux, IC Gillberg, H Soderstrom, B Giros… - Nature …, 2003 - nature.com
Many studies have supported a genetic etiology for autism. Here we report mutations in two
X-linked genes encoding neuroligins NLGN3 and NLGN4 in siblings with autism-spectrum …

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

ML Bouthenet, E Souil, MP Martres, P Sokoloff, B Giros… - Brain research, 1991 - Elsevier
The messenger RNA (mRNA) of the recently characterized D 3 dopamine receptor was
visualized on rat brain sections using in situ hybridization with a 32 P-labeled ribonucleic acid …

A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons

…, P Ravassard, M Pohl, B Gasnier, B Giros… - Journal of …, 2002 - Soc Neuroscience
Two proteins previously known as Na + -dependent phosphate transporters have been
identified recently as vesicular glutamate transporters (VGLUT1 and VGLUT2). Together, …

[PDF][PDF] The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons

…, C Bedet, B Gasnier, B Giros… - The Journal of …, 2001 - Soc Neuroscience
Before their exocytotic release during stimulation of nerve terminals, nonpeptide neurotransmitters
are loaded into synaptic vesicles by specific transporters. Recently, a protein initially …

Alternative splicing directs the expression of two D2 dopamine receptor isoforms

B Giros, P Sokoloff, MP Martres, JF Riou, LJ Emorine… - Nature, 1989 - nature.com
DOPAMINE receptors are classified into D l and D 2 subtypes on the basis of their
pharmacological properties and the intracellular responses they mediate 1 . The cerebral D 2 …

Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H] hydroxy-N, N-di-n-propyl-2-aminotetralin.

…, J Diaz, C Pilon, MP Martres, B Giros… - Proceedings of the …, 1992 - National Acad Sciences
We have identified 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin ([3H]7-OH-DPAT) as a
selective probe for the recently cloned dopamine D3 receptor and used it to assess the …