Generalized epilepsy with febrile seizures plus type 2 (GEFS+ 2, MIM 604233) is an autosomal
dominant disorder characterized by febrile seizures in children and afebrile seizures in …

Progressive myoclonus epilepsy of the Unverricht–Lundborg type (EPM1; MIM 254800) is
an autosomal recessive disorder with onset between 6 and 13 years followed by variable …

Genetic factors, specially those related to serotoninergic activities, and childhood maltreatment
have both been implicated in suicidal behaviour (SB). However, little attention has been …

Progressive myoclonus epilepsy (EPM1) is an autosomal recessive disorder, characterized
by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The EPM1 locus was …

Background Genes encoding proteins involved in serotonergic metabolism are major candidates
in association studies of mood disorders and suicidal behavior. This association study …

The basis of suicidal behavior (SB) is complex and multifactorial. Numerous risk factors have
been identified. Epidemiological genetics studies (family studies, twin studies, adoption …

BACKGROUND: In the first year following a suicide attempt, patients are at high risk for
reattempt and for completed suicide. We aim to determine the predictive value of two serotonin-…

Over the past few years, studies of DNA isolated from human fossils and archaeological
remains have generated considerable novel insight into the history of our species. Several …

We report the identification of a new locus for generalized epilepsy with febrile seizures plus
(GEFS+). Six family members manifested isolated typical febrile seizures (FS), and five had …

OBJECTIVE: Although genetic factors have been implicated in the etiology of bipolar disorder,
no specific gene has been conclusively identified. Given the link between abnormalities in …