BackgroundThe neuropharmacological actions of antidepressants are well characterised
but our understanding of how these changes translate into improved mood are still emerging.…

BackgroundSelective serotonin reuptake inhibitors (SSRIs) are typically thought to have a
delay of several weeks in the onset of their clinical effects. However, recent reports suggest …

OBJECTIVE: Antidepressants that inhibit the reuptake of serotonin (SSRIs) or norepinephrine
(SNRIs) are effective in the treatment of disorders such as depression and anxiety. …

The fact that selective serotonin reuptake inhibitors (SSRIs) have antidepressant effects in
some patients supports the notion that serotonin plays a role in the mode of action of …

A negative bias in the deployment of attention to emotional stimuli is commonly found in both
anxiety and depression. Recent work has highlighted that such biases are causally related …

Background Psychological treatments occupy an important place in evidence-based mental
health treatments. Now is an exciting time to fuel treatment research: a pressing demand for …

There is growing interest in the effects of antidepressant drug treatment on measures of
emotional processing. Such actions may help us understand the role of monoamines in …

Objectives The present study explored the effects of two prebiotics on the secretion of the
stress hormone, cortisol and emotional processing in healthy volunteers. Methods Forty-five …

BACKGROUND: The amygdala is believed to play a key role in processing emotionally
salient, threat-relevant, events that require further online processing by cortical regions. …

Most currently available antidepressants target monoamine neurotransmitter function.
However, a purely neurotransmitter-based explanation for antidepressant drug action is …