Recent literature has pointed to the existence of inflammasome-mediated inflammatory
pathways in central nervous system (CNS) disorders and associated changes in behavior. …

The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

Hypercholesterolemia is associated with an increased risk of heart disease. The effect of
garlic on blood lipids has been studied in numerous trials and summarized in meta-analyses, …

The purpose of this randomized controlled trial was to determine the effects of resistance
training (RT) on markers of inflammation and immune function in breast cancer survivors. Thirty-…

Historically the monoaminergic neurotransmitter system, in particular the serotonergic
system, was seen as being responsible for the pathophysiology of major depressive disorder (…

In multiple sclerosis, CD8 T-cells are thought play a key pathogenetic role, but mechanistic
evidence from rodent models is limited. Here, we have tested the encephalitogenic potential …

Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties
with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been …

Background: Preliminary research suggests that major depressive disorder (MDD) is associated
with structural alterations in the brain, as well as with low-grade peripheral inflammation…

Autoimmune processes are suspected to play a role in the pathophysiology of psychotic
disorders. Better understanding of the associations between auto-immunoglobulin G (IgG) …

Background Environmental enrichment (EE) has been shown to modulate behavior and
hippocampal gene expression; however, the currently available literature does not explain the …