User profiles for Charl Els

Charl Els

Clinical Professor, University of Alberta
Verified email at ualberta.ca
Cited by 1339

Adverse events associated with medium‐and long‐term use of opioids for chronic non‐cancer pain: an overview of Cochrane Reviews

C Els, TD Jackson, D Kunyk, VG Lappi… - Cochrane Database …, 2017 - cochranelibrary.com
Background Chronic pain is common and can be challenging to manage. Despite increased
utilisation of opioids, the safety and efficacy of long‐term use of these compounds for …

High‐dose opioids for chronic non‐cancer pain: an overview of Cochrane Reviews

C Els, TD Jackson, R Hagtvedt, D Kunyk… - Cochrane Database …, 2023 - cochranelibrary.com
Objectives To describe the evidence from Cochrane Reviews and overviews regarding the
efficacy and safety of high‐dose opioids (defined as 200 mg morphine equivalent or more per …

Varenicline: mode of action, efficacy, safety and accumulated experience salient for clinical populations

…, I Berlin, P Hajek, K Fagerström, C Els… - … medical research and …, 2020 - Taylor & Francis
Objective: Varenicline, a selective partial agonist of the α4β2 nicotinic acetylcholine receptor,
is a smoking cessation pharmacotherapy that more than doubles the chance of quitting …

ACOEM practice guidelines: opioids for treatment of acute, subacute, chronic, and postoperative pain

…, K Bowden, F Branco, K DuBrueler, C Els… - … of occupational and …, 2014 - journals.lww.com
Methods: Literature searches were performed using PubMed, EBSCO, Cochrane Review,
and Google Scholar without publication date limits. Of 264,617 articles' titles screened and …

[HTML][HTML] Flexible, dual-form nicotine replacement therapy or varenicline in comparison with nicotine patch for smoking cessation: a randomized controlled trial

HE Tulloch, AL Pipe, C Els, MJ Clyde, RD Reid - BMC medicine, 2016 - Springer
Background Extended use of combined pharmacotherapies to treat tobacco dependence
may increase smoking abstinence; few studies have examined their effectiveness. The …

[HTML][HTML] Human rights violations in organ procurement practice in China

NW Paul, A Caplan, ME Shapiro, C Els, KC Allison… - BMC Medical …, 2017 - Springer
Background Over 90% of the organs transplanted in China before 2010 were procured from
prisoners. Although Chinese officials announced in December 2014 that the country would …

Characteristics and prognostic factors for return to work in public safety personnel with work-related posttraumatic stress injury undergoing rehabilitation

…, C Brown, A Senthilselvan, S Straube, C Els… - Journal of occupational …, 2021 - Springer
Purpose Public safety personnel (PSP) are at risk of developing posttraumatic stress injury (PTSI)
due to exposure to traumatic experiences and accidents. Rehabilitation programs are …

[HTML][HTML] Historical development and current status of organ procurement from death-row prisoners in China

KC Allison, A Caplan, ME Shapiro, C Els, NW Paul… - BMC medical …, 2015 - Springer
Background In December 2014, China announced that only voluntarily donated organs
from citizens would be used for transplantation after January 1, 2015. Many medical …

ACOEM practice guidelines: opioids and safety-sensitive work

…, K Bowden, F Branco, K DuBrueler, C Els… - … of occupational and …, 2014 - journals.lww.com
Objective: ACOEM has updated the treatment guidelines concerning opioids. This report
highlights the safety-sensitive work recommendation that has been developed. Methods: …

A bidirectional path analysis model of smoking cessation self‐efficacy and concurrent smoking status: Impact on abstinence outcomes

M Clyde, A Pipe, R Reid, C Els, H Tulloch - Addiction biology, 2019 - Wiley Online Library
Self‐efficacy is routinely associated with abstinence in the addictions literature, and is a
major component relapse‐prevention models. The magnitude of this relationship has been …