User profiles for Christian Waeber
 | Christian WaeberUniversity College Cork Verified email at ucc.ie Cited by 29897 |
Differential signal transduction by five splice variants of the PACAP receptor
D Spongier, C Waeber, C Pantaloni, F Holsboer… - Nature, 1993 - nature.com
THE two forms of pituitary adenylyl cyclase-activating polypeptide (PACAP-27 and -38) are
neuropeptides of the secretin/glucagon/ vasoactive intestinal polypeptide/growth-hormone-…
neuropeptides of the secretin/glucagon/ vasoactive intestinal polypeptide/growth-hormone-…
Ischemic brain injury is mediated by the activation of poly (ADP-ribose) polymerase
Poly(ADP-ribose)polymerase (PARP, EC 2.4.2.30), an abundant nuclear protein activated
by DNA nicks, mediates cell death in vitro by nicotinamide adenine dinucleotide (NAD) …
by DNA nicks, mediates cell death in vitro by nicotinamide adenine dinucleotide (NAD) …
Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
…, M Shimizu-Sasamata, C Waeber… - Journal of Cerebral …, 1998 - journals.sagepub.com
Inhibitors of apoptosis and of excitotoxic cell death reduce brain damage after transient and
permanent middle cerebral artery occlusion. We compared the neuroprotective effects of two …
permanent middle cerebral artery occlusion. We compared the neuroprotective effects of two …
FGF-2 regulation of neurogenesis in adult hippocampus after brain injury
Fibroblast growth factor-2 (FGF-2) promotes proliferation of neuroprogenitor cells in culture
and is up-regulated within brain after injury. Using mice genetically deficient in FGF-2 (FGF-2 …
and is up-regulated within brain after injury. Using mice genetically deficient in FGF-2 (FGF-2 …
Migraine as an inflammatory disorder
C Waeber, MA Moskowitz - Neurology, 2005 - AAN Enterprises
… Christian Waeber, PhD, and Michael A. Moskowitz, MD… Waeber C. The role of 5-HT1B/1D
receptors in the treatment of migraine. CNS Spectrums 1998;3:30–39. … Christian Waeber, PhD …
receptors in the treatment of migraine. CNS Spectrums 1998;3:30–39. … Christian Waeber, PhD …
Delayed inflammation in rat meninges: implications for migraine pathophysiology
…, R Letourneau, TC Theoharides, C Waeber… - Brain, 2001 - academic.oup.com
Nitric oxide (NO) has been implicated in migraine pathogenesis based on the delayed
development of typical migraine headache 4–6 h after infusing the NO donor nitroglycerin […
development of typical migraine headache 4–6 h after infusing the NO donor nitroglycerin […
Microemboli may link spreading depression, migraine aura, and patent foramen ovale
Objective Patent foramen ovale and pulmonary arteriovenous shunts are associated with
serious complications such as cerebral emboli, stroke, and migraine with aura. The …
serious complications such as cerebral emboli, stroke, and migraine with aura. The …
[HTML][HTML] Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1
Familial hemiplegic migraine type 1 (FHM1) is an autosomal dominant subtype of migraine
with aura that is associated with hemiparesis. As with other types of migraine, it affects …
with aura that is associated with hemiparesis. As with other types of migraine, it affects …
Fingolimod provides long‐term protection in rodent models of cerebral ischemia
Objective: The sphingosine‐1‐phosphate (S1P) receptor agonist fingolimod (FTY720), that
has shown efficacy in advanced multiple sclerosis clinical trials, decreases reperfusion injury …
has shown efficacy in advanced multiple sclerosis clinical trials, decreases reperfusion injury …
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death
After mild ischemic insults, many neurons undergo delayed neuronal death. Aberrant
activation of the cell cycle machinery is thought to contribute to apoptosis in various conditions …
activation of the cell cycle machinery is thought to contribute to apoptosis in various conditions …