Controlling cell behavior electrically: current views and future potential

CD McCaig, AM Rajnicek, B Song… - Physiological …, 2005 - journals.physiology.org
Direct-current (DC) electric fields are present in all developing and regenerating animal
tissues, yet their existence and potential impact on tissue repair and development are largely …

Electrical dimensions in cell science

CD McCaig, B Song, AM Rajnicek - Journal of cell science, 2009 - journals.biologists.com
Cells undergo a variety of physiological processes, including division, migration and
differentiation, under the influence of endogenous electrical cues, which are generated …

Physiological electrical fields modify cell behaviour

CD McCaig, M Zhao - Bioessays, 1997 - Wiley Online Library
Steady direct current (dc) electric fields exist in many biological systems over many hours. At
these times cells are dividing, differentiating, moving to final locations and extending motile …

Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN

…, JV Forrester, HR Bourne, PN Devreotes, CD McCaig… - Nature, 2006 - nature.com
Wound healing is essential for maintaining the integrity of multicellular organisms. In every
species studied, disruption of an epithelial layer instantaneously generates endogenous …

Contact guidance of CNS neurites on grooved quartz: influence of groove dimensions, neuronal age and cell type

…, S Britland, CD McCaig - Journal of cell science, 1997 - journals.biologists.com
… Rajnicek, Stephen Britland, Colin D. McCaig; Contact guidance of CNS neurites on grooved
… cellular mechanisms for contact guidance of growth cones (Rajnicek and McCaig, 1997b). …

Electrical stimulation directly induces pre-angiogenic responses in vascular endothelial cells by signaling through VEGF receptors

…, E Wang, JV Forrester, CD McCaig - Journal of cell …, 2004 - journals.biologists.com
… Forrester, Colin D. McCaig; Electrical stimulation directly induces pre-angiogenic responses
in vascular endothelial cells by signaling through VEGF receptors. J Cell Sci 22 January …

Electrical cues regulate the orientation and frequency of cell division and the rate of wound healing in vivo

…, M Zhao, JV Forrester, CD McCaig - Proceedings of the …, 2002 - National Acad Sciences
Controlling cell division is fundamental. One environmental cue that exerts profound control
over both the orientation and frequency of cell division in vivo is a naturally occurring, wound…

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1

…, O Hurko, CD McCaig, G Riedel, D St Clair - Journal of …, 2008 - Soc Neuroscience
Disrupted-in-Schizophrenia-1 (DISC1), identified by positional cloning of a balanced translocation
(1;11) with the breakpoint in intron 8 of a large Scottish pedigree, is associated with a …

Membrane lipids, EGF receptors, and intracellular signals colocalize and are polarized in epithelial cells moving directionally in a physiological electric field

M Zhao, J Pu, JV Forrester, CD McCaig - The FASEB Journal, 2002 - Wiley Online Library
Directed cell migration is essential for tissue formation, inflammation, and wound healing.
Chemotaxis plays a major role in these situations and is underpinned by asymmetric …

Orientation and directed migration of cultured corneal epithelial cells in small electric fields are serum dependent

…, JV Forrester, CD McCaig - Journal of cell …, 1996 - journals.biologists.com
… Forrester, Colin D. McCaig; Orientation and directed migration of cultured corneal epithelial
cells in small electric fields are serum dependent. J Cell Sci 1 June 1996; 109 (6): 1405–…