Background Diagnostic tools for liver disease can now include estimation of the grade of
hepatic steatosis (S0 to S3). Controlled attenuation parameter (CAP) is a non-invasive method …

Objective Antidepressant drugs can cause drug-induced liver injury (DILI). The authors review
clinical data relevant to antidepressant-induced liver injury and provide recommendations …

Objective Chronic alcohol consumption is an important cause of liver-related deaths. Specific
intestinal microbiota profiles are associated with susceptibility or resistance to alcoholic …

Background Intestinal microbiota plays an important role in bile acid homeostasis. Aim To
study the structure of the intestinal microbiota and its function in bile acid homeostasis in …

Excessive alcohol consumption leads to severe alcoholic hepatitis (sAH) or chronic alcoholic
pancreatitis (CAP) only in a subset of patients. We aimed to characterize the intestinal …

Background and aim Sarcopenic obesity is a risk factor of morbidity and mortality. The aim
of this study was to generate a predictive score of sarcopenia occurrence one year after …

Background & Aims The reliability of transient elastography ( TE ) to assess liver fibrosis is
insufficiently validated in alcoholic liver disease ( ALD ). We aimed to validate the diagnostic …

Background & Aims Kupffer cells (KC) play a key role in the onset of inflammation in non-alcoholic
steatohepatitis (NASH). The glucocorticoid receptor (GR) induces glucocorticoid-…

Background: The microbiota interacts with the brain through the gut–brain axis, and a
distinct dysbiosis may lead to major depressive episodes. Bacteria can pass through the gut …

Hepatic resection is the gold standard for patients affected by primary or metastatic liver
tumors but is hampered by the risk of post-hepatectomy liver failure. Despite recent …