[HTML][HTML] Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta …
Background The profile of cortical neuroanatomical abnormalities in schizophrenia is not
fully understood, despite hundreds of published structural brain imaging studies. This study …
fully understood, despite hundreds of published structural brain imaging studies. This study …
Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia
…, TM Hyde, C Shannon-Weickert… - Proceedings of the …, 2004 - National Acad Sciences
GRM3, a metabotropic glutamate receptor-modulating synaptic glutamate, is a promising
schizophrenia candidate gene. In a family-based association study, a common GRM3 …
schizophrenia candidate gene. In a family-based association study, a common GRM3 …
Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease
AJ Law, BK Lipska, CS Weickert… - Proceedings of the …, 2006 - National Acad Sciences
Genetic variation in neuregulin 1 (NRG1) is associated with schizophrenia. The disease-associated
SNPs are noncoding, and their functional implications remain unknown. We …
SNPs are noncoding, and their functional implications remain unknown. We …
Human dysbindin (dtnbp1) gene expression innormal brain and in schizophrenic prefrontal cortex and midbrain
CS Weickert, RE Straub, BW McClintock… - Archives of general …, 2004 - jamanetwork.com
Context The schizophrenia-susceptibility gene dysbindin (DTNBP1on 6p22.3) encodes a
neuronal protein that binds to β-dystrobrevin and may be part of the dystrophin protein complex…
neuronal protein that binds to β-dystrobrevin and may be part of the dystrophin protein complex…
Expression of interneuron markers in the dorsolateral prefrontal cortex of the developing human and in schizophrenia
…, C Duncan, M Elashoff, CS Weickert - American Journal of …, 2010 - Am Psychiatric Assoc
Objective: The onset of schizophrenia symptoms in late adolescence implies a neurodevelopmental
trajectory for the disease. Indeed, the γ-aminobutyric acid (GABA) inhibitory system …
trajectory for the disease. Indeed, the γ-aminobutyric acid (GABA) inhibitory system …
Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders
MT Ray, CS Weickert, E Wyatt, MJ Webster - Journal of Psychiatry and …, 2011 - jpn.ca
Background: Brain-derived neurotrophic factor (BDNF), tyrosine kinase receptor (trkB-TK+)
and glutamic acid decarboxylase (GAD 67 ) mRNA levels have previously been found to be …
and glutamic acid decarboxylase (GAD 67 ) mRNA levels have previously been found to be …
Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in …
…, DR Weinberger, CS Weickert - Human molecular …, 2007 - academic.oup.com
The neuregulin 1 ( NRG1 ) receptor, ErbB4 , has been identified as a potential risk gene for
schizophrenia. HER4/ErbB4 is a receptor tyrosine kinase whose transcript undergoes …
schizophrenia. HER4/ErbB4 is a receptor tyrosine kinase whose transcript undergoes …
Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia
BK Lipska, A Deep-Soboslay, CS Weickert, TM Hyde… - Biological …, 2006 - Elsevier
BACKGROUND: Studies of postmortem human brain are important for investigating underlying
pathogenic molecular mechanisms of neuropsychiatric disorders. They are, however, …
pathogenic molecular mechanisms of neuropsychiatric disorders. They are, however, …
Role of ATP‐binding cassette transporters in brain lipid transport and neurological disease
WS Kim, CS Weickert, B Garner - Journal of neurochemistry, 2008 - Wiley Online Library
The brain is lipid‐rich compared to other organs and although previous studies have
highlighted the importance of ATP‐binding cassette (ABC) transporters in the regulation of lipid …
highlighted the importance of ATP‐binding cassette (ABC) transporters in the regulation of lipid …
[HTML][HTML] Rethinking schizophrenia in the context of normal neurodevelopment
…, SY Tsai, TW Weickert, C Shannon Weickert - Frontiers in cellular …, 2013 - frontiersin.org
The schizophrenia brain is differentiated from the normal brain by subtle changes, with
significant overlap in measures between normal and disease states. For the past 25 years, …
significant overlap in measures between normal and disease states. For the past 25 years, …