User profiles for David A. McCormick

David A. McCormick

Professor, University of Oregon; Professor Emeritus, Yale University
Verified email at uoregon.edu
Cited by 55511

Cellular and network mechanisms of rhythmic recurrent activity in neocortex

MV Sanchez-Vives, DA McCormick - Nature neuroscience, 2000 - nature.com
The neocortex generates periods of recurrent activity, such as the slow (0.1–0.5 Hz) oscillation
during slow-wave sleep. Here we demonstrate that slices of ferret neocortex maintained …

Thalamocortical oscillations in the sleeping and aroused brain

M Steriade, DA McCormick, TJ Sejnowski - Science, 1993 - science.org
Sleep is characterized by synchronized events in billions of synaptically coupled neurons in
thalamocortical systems. The activation of a series of neuromodulatory transmitter systems …

Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex

DA McCormick, BW Connors… - Journal of …, 1985 - journals.physiology.org
Slices of sensorimotor and anterior cingulate cortex from guinea pigs were maintained in vitro
and bathed in a normal physiological medium. Electrophysiological properties of neurons …

Sleep and arousal: thalamocortical mechanisms

DA McCormick, T Bal - Annual review of neuroscience, 1997 - annualreviews.org
▪ Abstract Thalamocortical activity exhibits two distinct states: (a) synchronized rhythmic activity
in the form of delta, spindle, and other slow waves during EEG-synchronized sleep and (b…

Properties of a hyperpolarization‐activated cation current and its role in rhythmic oscillation in thalamic relay neurones.

DA McCORMICK, HC Pape - The Journal of physiology, 1990 - Wiley Online Library
1. The physiological and functional features of time‐dependent anomalous rectification
activated by hyperpolarization and the current which underlies it, Ih, were examined in guinea‐…

Neurotransmitter control of neocortical neuronal activity and excitability

DA McCormick, Z Wang, J Huguenard - Cerebral cortex, 1993 - academic.oup.com
The pattern of activity and excitability of cortical neurons and neuronal circuits is dependent
upon the interaction between glutamatergic and GABAergic fast-activating transmitter …

On the cellular and network bases of epileptic seizures

DA McCormick, D Contreras - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract The highly interconnected networks of the mammalian forebrain can generate a
wide variety of synchronized activities, including those underlying epileptic seizures, which …

Turning on and off recurrent balanced cortical activity

Y Shu, A Hasenstaub, DA McCormick - Nature, 2003 - nature.com
The vast majority of synaptic connections onto neurons in the cerebral cortex arise from
other cortical neurons, both excitatory and inhibitory, forming local and distant ‘recurrent’ …

[PDF][PDF] Rapid neocortical dynamics: cellular and network mechanisms

B Haider, DA McCormick - Neuron, 2009 - cell.com
The highly interconnected local and large-scale networks of the neocortical sheet rapidly and
dynamically modulate their functional connectivity according to behavioral demands. This …

Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition

…, AR Hasenstaub, DA McCormick - Journal of …, 2006 - Soc Neuroscience
The recurrent excitatory and inhibitory connections between and within layers of the cerebral
cortex are fundamental to the operation of local cortical circuits. Models of cortical function …