Excitatory projections from the prefrontal cortex (PFC) to the ventral tegmental area (VTA)
play an important role in regulating the activity of VTA neurons and the extracellular levels of …

Beginning with a brief description of mature anatomic pathways and neurotransmitters in the
“pain system,” this article details their development in the human fetus, neonate, and child. …

For normal regulation of motor, affective, and cognitive functions, dopamine provides an
essential modulation of glutamate transmission within multiple brain regions. This paper will …

Dopamine‐containing projections from the ventral tegmental area (VTA) to the prefrontal
cortex (PFC) have been extensively characterized since their discovery over 25 years ago. …

Several factors led to the development of the guide. Recent studies have revealed that the
public increasingly believes it is the physician’s responsibility to assess and counsel their …

Objective To compare ratings of patients referred for geriatric evaluation and their proxies
with respect to patients' ability to perform activities of daily living. Design Retrospective chart …

Objectives: To longitudinally assess on‐road driving performance in healthy older adults
and those with early‐stage dementia of the Alzheimer type (DAT). Design: A prospective …

Afferents to the prefrontal cortex (PFC) from the hippocampal formation and from midbrain
dopamine (DA) neurons have been implicated in the cognitive and adaptive functions of this …

Dopamine (DA) neurons in the substantia nigra (SN) and ventral tegmental area (VTA) form
several projection systems with diverse functions, such as motor planning through the …

Article abstract Self-reported versus informant-reported memory problems in nondemented
elderly adults and in individuals with very mild and mild dementia of the Alzheimer type (DAT…