A balanced (1;11)(q42.1;q14.3) translocation segregates with schizophrenia and related
psychiatric disorders in a large Scottish family (maximum LOD = 6.0). We hypothesize that the …

The development of trait markers of schizophrenia would represent an important advance in
understanding the genetic architecture of the disease. To date, no candidate markers have …

Context Recent studies suggest that copy number variation in the human genome is extensive
and may play an important role in susceptibility to disease, including neuropsychiatric …

• Several psychophysiological abnormalities associated with schizophrenia have been
proposed as genetic trait markers of vulnerability to the disorder. Smooth pursuit eye tracking …

The main clinical feature of bipolar affective disorder is a change of mood to depression or
elation. Unipolar disorder, also termed majc depressive disorder, describes the occurrence c …

Long-latency auditory event-related potentials were examined in 96 subjects with schizophrenia,
99 with bipolar affective disorder and 48 with major depressive (unipolar) disorder, and …

Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology
of major mental illness. Furthermore, many of its protein-binding partners show evidence for …

The P300 (P3) and other long latency auditory evoked potentials were measured in 15
patients with presenile dementia Alzheimer type (ATD), 16 patients with alcoholic Korsakoff …

P300 (P3) and other long latency auditory event-related potentials (ERPs) were recorded in
33 adults with fragile X syndrome. All patients had an abnormal P3. It was longer in latency …

This study was designed to investigate whether auditory P300 event-related potential and
smooth pursuit eye-movement abnormalities in schizophrenia are associated with brain …