Although plasma proteins have important roles in biological processes and are the direct
targets of many drugs, the genetic factors that control inter-individual variation in plasma …

The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is
associated with multiple complex diseases. The genetic determinants of chronic inflammation …

Alcohol consumption is a moderately heritable trait, but the genetic basis in humans is
largely unknown, despite its clinical and societal importance. We report a genome-wide …

Circulating proteins have important functions in inflammation and a broad range of diseases.
To identify genetic influences on inflammation-related proteins, we conducted a genome-…

We report the results of a study investigating the influence of elevated CO 2 on species
interactions across three trophic levels: a plant (Brassica oleracea), two aphid herbivores (the …

Background Major depressive disorder (MDD) is a stress-related psychiatric disorder. A
subgroup of MDD patients is characterized by increased inflammatory activation. We aimed to …

Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids
and proteins through genome-wide association studies represents a powerful means of …

The firing of mesolimbic dopamine neurons is important for drug-induced reinforcement,
although underlying genetic factors remain poorly understood. In a recent genome-wide …

To study mental illness and health, in the past researchers have often broken down their
complexity into individual subsystems (eg, genomics, transcriptomics, proteomics, clinical data) …