Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
KP Lesch, D Bengel, A Heils, SZ Sabol, BD Greenberg… - Science, 1996 - science.org
Transporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been implicated
in anxiety in humans and animal models and is the site of action of widely used uptake-…
in anxiety in humans and animal models and is the site of action of widely used uptake-…
Allelic variation of human serotonin transporter gene expression
…, S Petri, G Stöber, P Riederer, D Bengel… - Journal of …, 1996 - Wiley Online Library
Mood, emotion, cognition, and motor functions as well as circadian and neuroendocrine
rhythms, including food intake, sleep, and reproductive activity, are modulated by the midbrain …
rhythms, including food intake, sleep, and reproductive activity, are modulated by the midbrain …
Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine (“Ecstasy”) in serotonin transporter-deficient mice
D Bengel, DL Murphy, AM Andrews, CH Wichems… - Molecular …, 1998 - ASPET
The sodium-dependent, high affinity serotonin [5-hydroxytryptamine (5-HT)] transporter (5-HTT)
provides the primary mechanism for inactivation of 5-HT after its release into the synaptic …
provides the primary mechanism for inactivation of 5-HT after its release into the synaptic …
Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
…, TJ Tolliver, SJ Huang, Q Li, D Bengel… - American journal of …, 1999 - Wiley Online Library
The human serotonin transporter (5‐HTT), encoded by a single gene on chromosome 17q11.2,
is expressed in brain and blood cells. 5‐HTT is implicated in mood and anxiety regulation…
is expressed in brain and blood cells. 5‐HTT is implicated in mood and anxiety regulation…
Role of the serotonin transporter promoter polymorphism in anxiety-related traits
…, J Lappalainen, JC Long, D Bengel… - Archives of General …, 1998 - jamanetwork.com
Background The heritability of interindividual variation in anxiety and other aspects of
personality establishes that variants of genes influence these traits. A functional polymorphism in …
personality establishes that variants of genes influence these traits. A functional polymorphism in …
Cellular localization and expression of the serotonin transporter in mouse brain
D Bengel, O Jöhren, AM Andrews, A Heils, R Mößner… - Brain research, 1997 - Elsevier
The high-affinity serotonin (5-HT) transporter (5-HTT) plays an important role in the removal
of extracellular serotonin, thereby modulating and terminating the action of this …
of extracellular serotonin, thereby modulating and terminating the action of this …
Gene structure and 5′-flanking regulatory region of the murine serotonin transporter
D Bengel, A Heils, S Petri, M Seemann, K Glatz… - Molecular brain …, 1997 - Elsevier
By modulating the magnitude and duration of postsynaptic responses, carrier-facilitated
serotonin (5-HT) transport into and release from the presynaptic neuron is central to the fine …
serotonin (5-HT) transport into and release from the presynaptic neuron is central to the fine …
[HTML][HTML] A biochemical marker panel in MRI-proven hyperacute ischemic stroke-a prospective study
C Knauer, K Knauer, S Müller, AC Ludolph, D Bengel… - BMC neurology, 2012 - Springer
Background Computer tomography (CT) is still the fastest and most robust technique to rule
out ICH in acute stroke. However CT-sensitivity for detection of ischemic stroke in the …
out ICH in acute stroke. However CT-sensitivity for detection of ischemic stroke in the …
Serotonin transporter (5‐HTT) gene and bipolar affective disorder
…, G Turner, JA Badner, D Bengel… - American journal of …, 1998 - Wiley Online Library
Interactions with antidepressants, as well as other biochemical evidence, implicate the
serotonin transporter 5‐HTT in the etiology of affective disorders. However, genetic studies have …
serotonin transporter 5‐HTT in the etiology of affective disorders. However, genetic studies have …
Long-term outcome in transient global amnesia patients with and without focal hyperintensities in the CA1 region of the hippocampus
I Uttner, S Prexl, W Freund, A Unrath, D Bengel… - European …, 2012 - karger.com
Focal hippocampal diffusion-weighted imaging (DWI) lesion patterns are detected in transient
global amnesia (TGA) patients in different frequency. It has been speculated that acute …
global amnesia (TGA) patients in different frequency. It has been speculated that acute …