Thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA) is currently the
only FDA-approved drug for acute ischemic stroke. However, its administration is still limited …

Background and Purpose— Experimental models of cerebral ischemia demonstrate that the
decrease in the caveolin-1 membrane protein results in an increase in endothelial …

Purpose Obesity during childhood has become a pandemic disease, mainly caused by a
diet rich in sugars and fatty acids. Among other negative effects, these diets can induce …

Deep brain stimulation (DBS) of reward system brain areas, such as the medial forebrain
bundle (MFB), by means of intracranial self-stimulation (ICSS), facilitates learning and memory …

Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the only pharmacological
approved treatment for ischemic stroke, despite its associated increasing risk of …

Intracranial self-stimulation (SS) in the lateral hypothalamus, a rewarding deep-brain stimulation,
is able to improve acquisition and retention of implicit and explicit memory tasks in rats. …

Intracranial Self-Stimulation (ICSS) at the medial forebrain bundle consistently facilitates
learning and memory in rats when administered post-training or when administered non-…

The electrical stimulation of specific brain targets has been shown to induce striking
antidepressant effects. Despite that recent data have indicated that cerebellum is involved in …

Background The assessment of deep brain stimulation (DBS) as a therapeutic alternative
for treating Alzheimer disease (AD) is ongoing. We aimed to determine the effects of …

Intracranial self-stimulation (ICSS) of the medial forebrain bundle is an effective treatment to
facilitate memory. Performance in both explicit and implicit memory tasks has been …