Studies on [3H] CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with …
A number of studies suggested that cannabis use can cause or exacerbate psychoses and
may increase the risk of developing schizophrenia. These findings suggest that changes in …
may increase the risk of developing schizophrenia. These findings suggest that changes in …
Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia
…, M McLeod, D Keriakous, J McKenzie, E Scarr - Molecular …, 2002 - nature.com
To test the hypothesis that muscarinic receptors are involved in the pathology of schizophrenia,
we measured muscarinic 1 (M1R) and muscarinic 4 (M4R) protein and mRNA as well as […
we measured muscarinic 1 (M1R) and muscarinic 4 (M4R) protein and mRNA as well as […
[HTML][HTML] Biomarkers in schizophrenia: a focus on blood based diagnostics and theranostics
CY Lai, E Scarr, M Udawela, I Everall… - World journal of …, 2016 - ncbi.nlm.nih.gov
Identifying biomarkers that can be used as diagnostics or predictors of treatment response (theranostics)
in people with schizophrenia (Sz) will be an important step towards being able …
in people with schizophrenia (Sz) will be an important step towards being able …
The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study
C Chavez, M Hollaus, E Scarr, G Pavey, A Gogos… - Brain research, 2010 - Elsevier
The aim of the present study was to elucidate the effect of estrogen on dopaminergic and
serotonergic regulation of prepulse inhibition (PPI) by measuring its effects on the density of …
serotonergic regulation of prepulse inhibition (PPI) by measuring its effects on the density of …
Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder
RE McCullumsmith, LV Kristiansen, M Beneyto, E Scarr… - Brain research, 2007 - Elsevier
Objectives: Schizophrenia is associated with dysfunction of glutamatergic neurotransmission,
and several studies have suggested glutamatergic abnormalities in bipolar disorder. …
and several studies have suggested glutamatergic abnormalities in bipolar disorder. …
[HTML][HTML] Cholinergic connectivity: it's implications for psychiatric disorders
E Scarr, AS Gibbons, J Neo, M Udawela… - Frontiers in cellular …, 2013 - frontiersin.org
Acetylcholine has been implicated in both the pathophysiology and treatment of a number
of psychiatric disorders, with most of the data related to its role and therapeutic potential …
of psychiatric disorders, with most of the data related to its role and therapeutic potential …
Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor …
L Gray, M Van Den Buuse, E Scarr… - International Journal …, 2009 - academic.oup.com
Abnormalities in glutamatergic signalling are proposed in schizophrenia in light of the
schizophreniform psychosis elicited by NMDA antagonists. The metabotropic glutamate receptor 5 …
schizophreniform psychosis elicited by NMDA antagonists. The metabotropic glutamate receptor 5 …
Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder
B Dean, N Tawadros, E Scarr, AS Gibbons - Journal of affective disorders, 2010 - Elsevier
BACKGROUND: From studies in the periphery, changed levels of tumour necrosis factor (TNF)
have been implicated in the pathophysiology of major depressive disorders (MDD). …
have been implicated in the pathophysiology of major depressive disorders (MDD). …
Biomarkers for psychiatry: the journey from fantasy to fact, a report of the 2013 CINP think tank
E Scarr, MJ Millan, S Bahn, A Bertolino… - International Journal …, 2015 - academic.oup.com
Background: A think tank sponsored by the Collegium Internationale Neuropsychopharmacologium
(CINP) debated the status and prospects of biological markers for psychiatric …
(CINP) debated the status and prospects of biological markers for psychiatric …
Phospholipase C-β1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration
CE McOmish, E Burrows, M Howard, E Scarr… - Molecular …, 2008 - nature.com
Phospholipase C-β1 (PLC-β1) is a rate-limiting enzyme implicated in postnatal-cortical
development and neuronal plasticity. PLC-β1 transduces intracellular signals from specific …
development and neuronal plasticity. PLC-β1 transduces intracellular signals from specific …
